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Self-collected cervicovaginal sampling for site-of-care primary HPV-based cervical cancer screening: a pilot study in a rural underserved Greek population.
Chatzistamatiou, Kimon; Chatzaki, Εkaterini; Constantinidis, Τheocharis; Nena, Evangelia; Tsertanidou, Athena; Agorastos, Theodoros.
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  • Chatzistamatiou K; a 4th Department of Obstetrics and Gynecology , Hippokratio Hospital of Thessaloniki , Thessaloniki , Greece.
  • Chatzaki Ε; b Laboratory of Pharmacology , Medical School, Democritus University of Thrace , Alexandroupolis , Greece.
  • Constantinidis Τ; c Peripheral Laboratory of Public Health , Hellenic Center for Disease Control and Prevention, Ministry of Health , Alexandroupolis , Greece.
  • Nena E; d Laboratory of Hygiene and Environmental Protection , Medical School, Democritus University of Thrace , Alexandroupolis , Greece.
  • Tsertanidou A; a 4th Department of Obstetrics and Gynecology , Hippokratio Hospital of Thessaloniki , Thessaloniki , Greece.
  • Agorastos T; a 4th Department of Obstetrics and Gynecology , Hippokratio Hospital of Thessaloniki , Thessaloniki , Greece.
J Obstet Gynaecol ; 37(8): 1059-1064, 2017 Nov.
Article en En | MEDLINE | ID: mdl-28631511
In the present pilot study, the feasibility of a site-of-care cervicovaginal self-sampling methodology for HPV-based screening was tested in 346 women residing in underserved rural areas of Northern Greece. These women provided self-collected cervicovaginal sample along with a study questionnaire. Following molecular testing, using the cobas® HPV Test, Roche®, HPV positive women, were referred to colposcopy and upon abnormal findings, to biopsy and treatment. Participation rate was 100%. Regular pap-test examination was reported for 17.1%. Among hrHPV testing, 11.9% were positive and colposcopy/biopsy revealed 2 CIN3 cases. Non-compliance was the most prevalent reason for no previous attendance. Most women reported non-difficulty and non-discomfort in self-sampling (77.6% and 82.4%, respectively). They would choose self-sampling over clinician-sampling (86.2%), and should self-sampling being available, they would test themselves more regularly (92.3%). In conclusion, self-sampling is feasible and well-accepted for HPV-based screening, and could increase population coverage in underserved areas, helping towards successful prevention.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Población Rural / Autocuidado / Manejo de Especímenes / Neoplasias del Cuello Uterino Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Aspecto: Determinantes_sociais_saude Límite: Adult / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Obstet Gynaecol Año: 2017 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Población Rural / Autocuidado / Manejo de Especímenes / Neoplasias del Cuello Uterino Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Aspecto: Determinantes_sociais_saude Límite: Adult / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: J Obstet Gynaecol Año: 2017 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido