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Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening.
Liu, Ming; Lo, Chun-Yeung; Wang, Guoxin; Chow, Hak-Fun; Ngo, Jacky Chi-Ki; Wan, David Chi-Cheong; Poon, Leo Lit-Man; Shaw, Pang-Chui.
Afiliación
  • Liu M; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Lo CY; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Wang G; Research Center of Plasmonic and Near-Infrared Science, Research Institute of Tsinghua University in Shenzhen, Shenzhen, China.
  • Chow HF; Department of Chemistry, Center of Novel Functional Molecules and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Hong Kong, China.
  • Ngo JC; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Wan DC; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Poon LL; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Shaw PC; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. Electronic address: pcshaw@cuhk.edu.hk.
Antiviral Res ; 144: 186-195, 2017 08.
Article en En | MEDLINE | ID: mdl-28629986
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus de la Influenza A / Proteínas Virales / Evaluación Preclínica de Medicamentos / Inhibidores Enzimáticos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Virus de la Influenza A / Proteínas Virales / Evaluación Preclínica de Medicamentos / Inhibidores Enzimáticos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos