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Multimorbidity and depression: A systematic review and meta-analysis.
Read, Jennifer R; Sharpe, Louise; Modini, Matthew; Dear, Blake F.
Afiliación
  • Read JR; University of Sydney, Australia.
  • Sharpe L; University of Sydney, Australia. Electronic address: louise.sharpe@sydney.edu.au.
  • Modini M; University of Sydney, Australia.
  • Dear BF; Macquarie University, Australia.
J Affect Disord ; 221: 36-46, 2017 10 15.
Article en En | MEDLINE | ID: mdl-28628766
BACKGROUND: Multimorbidity, the presence of two or more chronic conditions, is increasingly common and complicates the assessment and management of depression. The aim was to investigate the relationship between multimorbidity and depression. METHOD: A systematic literature search was conducted using the databases; PsychINFO, Medline, Embase, CINAHL and Cochrane Central. Results were meta-analysed to determine risk for a depressive disorder or depressive symptoms in people with multimorbidity. RESULTS: Forty articles were identified as eligible (n = 381527). The risk for depressive disorder was twice as great for people with multimorbidity compared to those without multimorbidity [RR: 2.13 (95% CI 1.62-2.80) p<0.001] and three times greater for people with multimorbidity compared to those without any chronic physical condition [RR: 2.97 (95% CI 2.06-4.27) p<0.001]. There was a 45% greater odds of having a depressive disorder with each additional chronic condition compared to the odds of having a depressive disorder with no chronic physical condition [OR: 1.45 (95% CI 1.28-1.64) p<0.001]. A significant but weak association was found between the number of chronic conditions and depressive symptoms [r = 0.26 (95% CI 0.18-0.33) p <0.001]. LIMITATIONS: Although valid measures of depression were used in these studies, the majority assessed the presence or absence of multimorbidity by self-report measures. CONCLUSIONS: Depression is two to three times more likely in people with multimorbidity compared to people without multimorbidity or those who have no chronic physical condition. Greater knowledge of this risk supports identification and management of depression.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Depresión / Trastorno Depresivo / Multimorbilidad Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Affect Disord Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Depresión / Trastorno Depresivo / Multimorbilidad Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Affect Disord Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Países Bajos