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Impact of hypoglycaemia on patient-reported outcomes from a global, 24-country study of 27,585 people with type 1 and insulin-treated type 2 diabetes.
Khunti, Kamlesh; Alsifri, Saud; Aronson, Ronnie; Cigrovski Berkovic, Maja; Enters-Weijnen, Catherine; Forsén, Tom; Galstyan, Gagik; Geelhoed-Duijvestijn, Petronella; Goldfracht, Margalit; Gydesen, Helge; Kapur, Rahul; Lalic, Nebojsa; Ludvik, Bernhard; Moberg, Erik; Pedersen-Bjergaard, Ulrik; Ramachandran, Ambady.
Afiliación
  • Khunti K; Diabetes Research Centre, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK. Electronic address: kk22@le.ac.uk.
  • Alsifri S; Al Hada Military Hospital, Taif 21944, Saudi Arabia. Electronic address: saudnafa@hotmail.com.
  • Aronson R; LMC Diabetes & Endocrinology, 1929 Bayview Ave, Suite 107, Toronto, ON M4G 3E8, Canada. Electronic address: Ronnie.Aronson@LMC.CA.
  • Cigrovski Berkovic M; University Hospital 'Sestre milosrdnice', Vinogradska cesta 29, Zagreb 10000, Croatia. Electronic address: maja.cigrovskiberkovic@gmail.com.
  • Enters-Weijnen C; Julius Clinical/Julius Center, UMC Utrecht, Broederplein 41, Zeist 3703 CD, The Netherlands. Electronic address: entersweijnen@juliusclinical.com.
  • Forsén T; Department of General Practice and Primary Health Care, University of Helsinki, Yliopistonkatu 4, Helsinki 00100, Finland. Electronic address: tom.forsen@fimnet.fi.
  • Galstyan G; Endocrinology Research Center, 1 Dmitriya Ulyanova str., Moscow 117036, Russian Federation; I.M.Sechenov First Moscow State Medical University, Moscow, Russia. Electronic address: mariagrishina2006@yandex.ru.
  • Geelhoed-Duijvestijn P; Medical Center Haaglanden, Westeinde Hospital, Lijnbaan 32, 2501 CK The Hague, The Netherlands. Electronic address: nel@icta3.com.
  • Goldfracht M; Clalit Health Services, Tel Aviv, and The Technion, 101 Arlozorov, Haifa, Israel. Electronic address: goldfrac@atcom.co.il.
  • Gydesen H; Novo Nordisk A/S, Vandtårnsvej 112, Søborg DK-2860, Denmark. Electronic address: hgy@novonordisk.com.
  • Kapur R; Novo Nordisk A/S, Vandtårnsvej 112, Søborg DK-2860, Denmark. Electronic address: RAHK@novonordisk.com.
  • Lalic N; Faculty of Medicine, University of Belgrade, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Dr Subotica 8, Belgrade 11 000, Serbia. Electronic address: nmlalic@eunet.rs.
  • Ludvik B; Rudolfstiftung Hospital and Medical University of Vienna, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030 Vienna, Austria. Electronic address: bernhard.ludvik@wienkav.at.
  • Moberg E; Karolinska Institutet, Solnavägen 1, 171 77 Solna, Stockholm, Sweden. Electronic address: Erik.Moberg@karolinska.se.
  • Pedersen-Bjergaard U; Nordsjællands Hospital Hillerød, Dyrehavevej 29, Hillerød 3400, Denmark. Electronic address: Ulrik.Pedersen-Bjergaard@regionh.dk.
  • Ramachandran A; India Diabetes Research Foundation and Dr A Ramachandran's Diabetes Hospitals, 110, Anna Salai, Guindy, Chennai 600032, India. Electronic address: ramachandran@vsnl.com.
Diabetes Res Clin Pract ; 130: 121-129, 2017 Aug.
Article en En | MEDLINE | ID: mdl-28602812
AIMS: Data on the impact of hypoglycaemia on patients' daily lives and diabetes self-management, particularly in developing countries, are lacking. The aim of this study was to assess fear of, and responses to, hypoglycaemia experienced by patients globally. MATERIALS AND METHODS: This non-interventional, multicentre, 4-week prospective study using self-assessment questionnaires and patient diaries consisted of 27,585 patients, ≥18years, with type 1 diabetes (n=8022) or type 2 diabetes (n=19,563) treated with insulin for >12months, at 2004 sites in 24 countries worldwide. RESULTS: Increased blood glucose monitoring (69.7%) and seeking medical assistance (62.0%) were the most common responses in the 4weeks following hypoglycaemic events for patients with type 1 diabetes and type 2 diabetes, respectively. Approximately 44% of patients with type 1 diabetes or type 2 diabetes increased calorie intake in response to a hypoglycaemic episode. Following hypoglycaemia, 3.9% (type 1 diabetes) and 6.2% (type 2 diabetes) of patients took leave from work or study. Regional differences in fear of, and responses to, hypoglycaemia were evident - in particular, a lower level of hypoglycaemic fear and utilisation of healthcare resources in Northern Europe and Canada. CONCLUSIONS: Hypoglycaemia has a major impact on patients and their behaviour. These global data for the first time reveal regional variations in response to hypoglycaemia and highlight the importance of patient education and management strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 1 / Diabetes Mellitus Tipo 2 / Miedo / Hipoglucemia / Insulina Tipo de estudio: Clinical_trials / Observational_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: America do norte / Europa Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 1 / Diabetes Mellitus Tipo 2 / Miedo / Hipoglucemia / Insulina Tipo de estudio: Clinical_trials / Observational_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: America do norte / Europa Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Irlanda