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From the Children's Oncology Group: Evidence-Based Recommendations for PEG-Asparaginase Nurse Monitoring, Hypersensitivity Reaction Management, and Patient/Family Education.
Woods, Deborah; Winchester, Kari; Towerman, Alison; Gettinger, Katie; Carey, Christina; Timmermann, Karen; Langley, Rachel; Browne, Emily.
Afiliación
  • Woods D; 1 Washington University, St. Louis, MO, USA.
  • Winchester K; 1 Washington University, St. Louis, MO, USA.
  • Towerman A; 1 Washington University, St. Louis, MO, USA.
  • Gettinger K; 1 Washington University, St. Louis, MO, USA.
  • Carey C; 1 Washington University, St. Louis, MO, USA.
  • Timmermann K; 1 Washington University, St. Louis, MO, USA.
  • Langley R; 1 Washington University, St. Louis, MO, USA.
  • Browne E; 2 St. Jude Children's Research Hospital, Memphis, TN, USA.
J Pediatr Oncol Nurs ; 34(6): 387-396, 2017.
Article en En | MEDLINE | ID: mdl-28602129
PEG-aspariginase is a backbone chemotherapy agent in pediatric acute lymphoblastic leukemia and in some non-Hodgkin lymphoma therapies. Nurses lack standardized guidelines for monitoring patients receiving PEG-asparaginase and for educating patients/families about hypersensitivity reaction risks. An electronic search of 6 databases using publication years 2000-2015 and multiple professional organizations and clinical resources was conducted. Evidence sources were reviewed for topic applicability. Each of the final 23 sources was appraised by 2 team members. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) system was used to assign a quality and strength rating for each recommendation. Multiple recommendations were developed: 4 relating to nurse monitoring of patients during and after drug administration, 8 guiding hypersensitivity reaction management, and 4 concerning patient/family educational content. These strong recommendations were based on moderate, low, or very-low-quality evidence. Several recommendations relied on generalized drug hypersensitivity guidelines. Additional research is needed to safely guide PEG-asparaginase monitoring, hypersensitivity reaction management, and patient/family education. Nurses administering PEG-asparaginase play a critical role in the early identification and management of hypersensitivity reactions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermería Oncológica / Educación del Paciente como Asunto / Cuidadores / Guías de Práctica Clínica como Asunto / Hipersensibilidad a las Drogas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: J Pediatr Oncol Nurs Asunto de la revista: ENFERMAGEM / NEOPLASIAS / PEDIATRIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermería Oncológica / Educación del Paciente como Asunto / Cuidadores / Guías de Práctica Clínica como Asunto / Hipersensibilidad a las Drogas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: J Pediatr Oncol Nurs Asunto de la revista: ENFERMAGEM / NEOPLASIAS / PEDIATRIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos