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Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.
Mimura, Yusuke; Katoh, Toshihiko; Saldova, Radka; O'Flaherty, Roisin; Izumi, Tomonori; Mimura-Kimura, Yuka; Utsunomiya, Toshiaki; Mizukami, Yoichi; Yamamoto, Kenji; Matsumoto, Tsuneo; Rudd, Pauline M.
Afiliación
  • Mimura Y; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan. mimuray66@outlook.jp.
  • Katoh T; Laboratory of Molecular Biology and Bioresponse, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Kitashirakawa, Oiwake-Cho, Sakyo-Ku, Kyoto, 606-8502, Japan.
  • Saldova R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.
  • O'Flaherty R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.
  • Izumi T; Center for Regenerative Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, 755-8505, Japan.
  • Mimura-Kimura Y; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.
  • Utsunomiya T; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.
  • Mizukami Y; Center for Gene Research, Yamaguchi University, 1-1-1 Minami-Kogushi, Ube, 755-8505, Japan.
  • Yamamoto K; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, 1-308 Suematsu, Nonoichi, Ishikawa, 921-8836, Japan.
  • Matsumoto T; Department of Clinical Research, NHO Yamaguchi-Ube Medical Center, 685 Higashi-Kiwa, Ube, 755-0241, Japan.
  • Rudd PM; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Mount Merrion, Blackrock, Dublin 4, Ireland.
Protein Cell ; 9(1): 47-62, 2018 01.
Article en En | MEDLINE | ID: mdl-28597152
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Ingeniería de Proteínas / Anticuerpos Monoclonales Límite: Animals / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Ingeniería de Proteínas / Anticuerpos Monoclonales Límite: Animals / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania