Sol-gel coated ion sources for liquid chromatography-direct electron ionization mass spectrometry.
Anal Chim Acta
; 978: 35-41, 2017 Jul 25.
Article
en En
| MEDLINE
| ID: mdl-28595724
Advances in interfacing liquid chromatography and electron ionization mass spectrometry are presented. New ion source coatings synthesized by sol-gel technology were developed and tested as vaporization surfaces in terms of peak intensity, peak width and peak delay for the liquid chromatography-direct electron ionization mass spectrometry (Direct-EI) determination of environmental pollutants like polycyclic aromatic hydrocarbons and steroids. Silica-, titania-, and zirconia-based coatings were sprayed inside the stainless steel ion source and characterized in terms of thermal stability, film thickness and morphology. Negligible weight losses until 350-400 °C were observed for all the materials, with coating thicknesses in the 6 (±1)-11 (±2) µm range for optimal ionization process. The best performances in terms of both peak intensity and peak width were obtained by using the silica-based coating: the detection of the investigated compounds was feasible at low ng µl-1 levels with a good precision (RSD < 9% for polycyclic aromatic hydrocarbons and <11% for hormones).
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Anal Chim Acta
Año:
2017
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Países Bajos