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Reproducibility of the plasma glucose response to moderate-intensity exercise in adolescents with Type 1 diabetes.
Abraham, M B; Davey, R J; Cooper, M N; Paramalingam, N; O'Grady, M J; Ly, T T; Jones, T W; Fournier, P A; Davis, E A.
Afiliación
  • Abraham MB; Department of Endocrinology and Diabetes, Princess Margaret Hospital, Perth, Australia.
  • Davey RJ; School of Paediatrics and Child Health, The University of Western Australia, Perth, Australia.
  • Cooper MN; School of Paediatrics and Child Health, The University of Western Australia, Perth, Australia.
  • Paramalingam N; Telethon Kids Institute, The University of Western Australia, Perth, Australia.
  • O'Grady MJ; Telethon Kids Institute, The University of Western Australia, Perth, Australia.
  • Ly TT; Department of Endocrinology and Diabetes, Princess Margaret Hospital, Perth, Australia.
  • Jones TW; School of Paediatrics and Child Health, The University of Western Australia, Perth, Australia.
  • Fournier PA; Telethon Kids Institute, The University of Western Australia, Perth, Australia.
  • Davis EA; Department of Endocrinology and Diabetes, Princess Margaret Hospital, Perth, Australia.
Diabet Med ; 34(9): 1291-1295, 2017 09.
Article en En | MEDLINE | ID: mdl-28586529
AIMS: The aim of the study was to evaluate the reproducibility of the plasma glucose response to moderate-intensity exercise performed on different days under controlled conditions in adolescents with Type 1 diabetes. METHODS: Eight adolescents with Type 1 diabetes on continuous subcutaneous insulin infusion completed two exercise sessions, each on two separate days, under basal insulin and fasting conditions. On each day, participants cycled twice for 30 min at 55% of their peak rate of oxygen consumption, with each exercise session separated by a 30-min rest. RESULTS: Plasma insulin levels were similar between testing days and exercise sessions. The mean absolute drop in plasma glucose from the commencement to the end of exercise was 1.6 ± 0.5 mmol/l on day 1 and 1.9 ± 0.7 mmol/l on day 2 (P = 0.3). In response to the first exercise session, plasma glucose levels relative to baseline did not change significantly (0.2 ± 0.6 and -0.2 ± 0.5 mmol/l on days 1 and 2). By contrast, the change in plasma glucose during the second exercise session was -1.1 ± 0.7 and -1.3 ± 0.7mmol/l on days 1 and 2, respectively. The mean absolute intra-individual difference in the change in plasma glucose between testing days were 0.7 ± 0.5 [95% confidence interval (CI) 0.4-1.0] and 0.7 ± 0.4 (95% CI 0.4-1.0) mmol/l, at the end of the first and second exercise sessions respectively. CONCLUSIONS: The plasma glucose response to moderate-intensity exercise under similar glycaemic and basal insulin conditions can be reproducible in adolescents with Type 1 diabetes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Ejercicio Físico / Diabetes Mellitus Tipo 1 Tipo de estudio: Clinical_trials Límite: Adolescent / Female / Humans / Male Idioma: En Revista: Diabet Med Asunto de la revista: ENDOCRINOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glucemia / Ejercicio Físico / Diabetes Mellitus Tipo 1 Tipo de estudio: Clinical_trials Límite: Adolescent / Female / Humans / Male Idioma: En Revista: Diabet Med Asunto de la revista: ENDOCRINOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido