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One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan.
Patel, Harilal; Patel, Prakash; Modi, Nirav; Shah, Shaival; Ghoghari, Ashok; Variya, Bhavesh; Laddha, Ritu; Baradia, Dipesh; Dobaria, Nitin; Mehta, Pavak; Srinivas, Nuggehally R.
Afiliación
  • Patel H; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Patel P; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Modi N; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Shah S; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Ghoghari A; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Variya B; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Laddha R; Pharmaceutical Technology Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Baradia D; Pharmaceutical Technology Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Dobaria N; Pharmaceutical Technology Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Mehta P; Pharmaceutical Technology Centre, Cadila Healthcare Limited, Ahmedabad, India.
  • Srinivas NR; Department of Drug Metabolism and Pharmacokinetics, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, India. Electronic address: nuggehally.srinivas@zyduscadila.com.
Eur J Pharm Sci ; 106: 87-93, 2017 Aug 30.
Article en En | MEDLINE | ID: mdl-28549679
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirrolidinas / Recolección de Muestras de Sangre / Triptaminas / Oxazolidinonas / Trastornos Migrañosos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirrolidinas / Recolección de Muestras de Sangre / Triptaminas / Oxazolidinonas / Trastornos Migrañosos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Pharm Sci Asunto de la revista: FARMACIA / FARMACOLOGIA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos