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Economic evaluation of the randomized European Achalasia trial comparing pneumodilation with Laparoscopic Heller myotomy.
Moonen, A; Busch, O; Costantini, M; Finotti, E; Tack, J; Salvador, R; Boeckxstaens, G; Zaninotto, G.
Afiliación
  • Moonen A; Department of Gastroenterology, Catholic University of Leuven, Leuven, Belgium.
  • Busch O; Gastrointestinal Surgery, Academic Medical Center, Amsterdam, The Netherlands.
  • Costantini M; Department of Surgical Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.
  • Finotti E; Department of Surgery, Policlinico di Abano Terme, Abano, Italy.
  • Tack J; Department of Gastroenterology, Catholic University of Leuven, Leuven, Belgium.
  • Salvador R; Department of Surgical Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy.
  • Boeckxstaens G; Department of Gastroenterology, Catholic University of Leuven, Leuven, Belgium.
  • Zaninotto G; Department of Academic Surgery, St Mary's Hospital, Imperial College, London, UK.
Neurogastroenterol Motil ; 29(11)2017 Nov.
Article en En | MEDLINE | ID: mdl-28547866
BACKGROUND: A recent multicenter randomized trial in achalasia patients has shown that pneumatic dilation resulted in equivalent relief of symptoms compared to laparoscopic Heller myotomy. Additionally, the cost of each treatment should be also taken in consideration. Therefore, the aim of the present study was to perform an economic analysis of the European achalasia trial. METHODS: Patients with newly diagnosed achalasia were enrolled from to 2003 to 2008 in 14 centers in five European countries and were randomly assigned to either pneumatic dilation (PD) or laparoscopic Heller (LHM). The economic analysis was performed in the three centers in three different countries where most patients were enrolled (Amsterdam [NL], Leuven, [B] and Padova [I]) and then applied to all patients included in the study. The total raw costs of the two treatments per patient include the initial costs, the costs of complications, and the costs of retreatments. RESULTS: Two hundred and one patients, 107 (57 males and 50 females, mean age 46 CI: 43-49 years) were randomized to LHM and 94 (59 males and 34 females, mean age 46 CI 43-50 years) to PD. The total cost of PD per patient was quite comparable in the three different centers; €3397 in Padova, €3259 in Amsterdam and €3792 in Leuven. For LHM, the total costs per patient were highest in Amsterdam: €4488 in Padova, €6720 in Amsterdam, and €5856 in Leuven. CONCLUSION: In conclusion, the strategy of treating achalasia starting with PD appears the most economic approach, independent of the health system.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acalasia del Esófago / Endoscopía del Sistema Digestivo / Dilatación / Miotomía de Heller Tipo de estudio: Clinical_trials / Evaluation_studies / Health_economic_evaluation Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Neurogastroenterol Motil Asunto de la revista: GASTROENTEROLOGIA / NEUROLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acalasia del Esófago / Endoscopía del Sistema Digestivo / Dilatación / Miotomía de Heller Tipo de estudio: Clinical_trials / Evaluation_studies / Health_economic_evaluation Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Neurogastroenterol Motil Asunto de la revista: GASTROENTEROLOGIA / NEUROLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido