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Cost-effectiveness analysis of endoscopic eradication therapy for treatment of high-grade dysplasia in Barrett's esophagus.
Filby, Alex; Taylor, Matthew; Lipman, Gideon; Lovat, Laurence; Haidry, Rehan.
Afiliación
  • Filby A; York Health Economic Consortium (YHEC), Enterprise House, Innovation Way, University of York, York, UK.
  • Taylor M; York Health Economic Consortium (YHEC), Enterprise House, Innovation Way, University of York, York, UK.
  • Lipman G; Department of Gastroenterology, University College Hospital, 235 Euston Rd, Fitzrovia, London, UK.
  • Lovat L; Department of Gastroenterology, University College Hospital, 235 Euston Rd, Fitzrovia, London, UK.
  • Haidry R; Department of Surgery & Interventional Sciences, University College London, London, UK.
J Comp Eff Res ; 6(5): 425-436, 2017 Jul.
Article en En | MEDLINE | ID: mdl-28541099
AIM: The aim was to evaluate the cost-effectiveness of endoscopic eradication therapy (EET) with combined endoscopic mucosal resection and radiofrequency ablation for the treatment of high-grade dysplasia (HGD) arising in patients with Barrett's esophagus compared with endoscopic surveillance alone in the UK. MATERIALS & METHODS: The cost-effectiveness model consisted of a decision tree and modified Markov model. A lifetime time horizon was adopted with the perspective of the UK healthcare system. RESULTS: The base case analysis estimates that EET for the treatment of HGD is cost-effective at a GB£20,000 cost-effectiveness threshold compared with providing surveillance alone for HGD patients (incremental cost-effectiveness ratio: GB£1272). CONCLUSION: EET is likely to be a cost-effective treatment strategy compared with surveillance alone in patients with HGD arising in Barrett's esophagus in the UK.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esófago de Barrett / Esofagoscopía / Ablación por Catéter Tipo de estudio: Evaluation_studies / Health_economic_evaluation / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: J Comp Eff Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esófago de Barrett / Esofagoscopía / Ablación por Catéter Tipo de estudio: Evaluation_studies / Health_economic_evaluation / Prognostic_studies Aspecto: Patient_preference Límite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: J Comp Eff Res Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido