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The PB2 mutation with lysine at 627 enhances the pathogenicity of avian influenza (H7N9) virus which belongs to a non-zoonotic lineage.
Li, Weixuan; Lee, Horace Hok Yeung; Li, Run Feng; Zhu, Huachen Maria; Yi, Guan; Peiris, Joseph Sriyal Malik; Yang, Zi Feng; Mok, Chris Ka Pun.
Afiliación
  • Li W; Department of clinical laboratory, First people's hospital of Foshan, Foshan, China.
  • Lee HHY; HKU-Pasteur Research Pole, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Li RF; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Zhu HM; Centre of Influenza Research, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Yi G; Centre of Influenza Research, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Peiris JSM; HKU-Pasteur Research Pole, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Yang ZF; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Mok CKP; Centre of Influenza Research, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Sci Rep ; 7(1): 2352, 2017 05 24.
Article en En | MEDLINE | ID: mdl-28539661

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Mutación Missense / Subtipo H7N9 del Virus de la Influenza A / Lisina Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Mutación Missense / Subtipo H7N9 del Virus de la Influenza A / Lisina Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido