[Intensive basic therapy decreases the need for drug treatment and improves glucose control: an important result of the diabetes intervention study]. / Intensivierte Basistherapie verringert die Notwendigkeit medikamentöser Behandlung und verbessert die Glukosekontrolle: ein wichtiges Ergebnis der Diabetesinterventionsstudie (DIS).
Z Gesamte Inn Med
; 43(24): 700-2, 1988 Dec 15.
Article
en De
| MEDLINE
| ID: mdl-2853497
In a period of five years in the diabetes intervention study (DIS), 1,139 diabetics aged 30-55 years, who in a 6-week screening phase had been classified as dietetically manageable, were treated in a controlled randomized study with intensified non-medicamentous basic therapy and--in a double blind trial--with 1,6 g clofibric acid. The essential components of the basic therapy were a fat-modified diet (so-called prudent diet) and recommendations for endurance training. Thus in comparison to the control group we succeeded in performing a ca. 40% decrease of the application of oral antidiabetic drugs. The fasting blood values were, nevertheless, with 155 mg% significantly lower than in the control group (169 mg%). Clofibric acid had no influence neither on the necessity to use insulin or oral antidiabetic drugs nor to the control of glycaemia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Modalidades de Fisioterapia
/
Clofibrato
/
Ácido Clofíbrico
/
Diabetes Mellitus Tipo 2
Tipo de estudio:
Clinical_trials
/
Guideline
Límite:
Humans
Idioma:
De
Revista:
Z Gesamte Inn Med
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Alemania