Your browser doesn't support javascript.
loading
Three-dimensional intrafractional internal target motions in accelerated partial breast irradiation using three-dimensional conformal external beam radiotherapy.
Hirata, Kimiko; Yoshimura, Michio; Mukumoto, Nobutaka; Nakamura, Mitsuhiro; Inoue, Minoru; Sasaki, Makoto; Fujimoto, Takahiro; Yano, Shinsuke; Nakata, Manabu; Mizowaki, Takashi; Hiraoka, Masahiro.
Afiliación
  • Hirata K; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
  • Yoshimura M; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan. Electronic address: myossy@kuhp.kyoto-u.ac.jp.
  • Mukumoto N; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
  • Nakamura M; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
  • Inoue M; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
  • Sasaki M; Clinical Radiology Service Division, Kyoto University Hospital, Japan.
  • Fujimoto T; Clinical Radiology Service Division, Kyoto University Hospital, Japan.
  • Yano S; Clinical Radiology Service Division, Kyoto University Hospital, Japan.
  • Nakata M; Clinical Radiology Service Division, Kyoto University Hospital, Japan.
  • Mizowaki T; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
  • Hiraoka M; Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.
Radiother Oncol ; 124(1): 118-123, 2017 07.
Article en En | MEDLINE | ID: mdl-28532607
PURPOSE: We evaluated three-dimensional intrafractional target motion, divided into respiratory-induced motion and baseline drift, in accelerated partial breast irradiation (APBI). METHODS: Paired fluoroscopic images were acquired simultaneously using orthogonal kV X-ray imaging systems at pre- and post-treatment for 23 patients who underwent APBI with external beam radiotherapy. The internal target motion was calculated from the surgical clips placed around the tumour cavity. RESULTS: The peak-to-peak respiratory-induced motions ranged from 0.6 to 1.5mm in all directions. A systematic baseline drift of 1.5mm towards the posterior direction and a random baseline drift of 0.3mm in the lateral-medial and cranial-caudal directions were observed. The baseline for an outer tumour cavity drifted towards the lateral and posterior directions, and that for an upper tumour cavity drifted towards the cranial direction. Moderate correlations were observed between the posterior baseline drift and the patients' physical characteristics. The posterior margin for intrafractional uncertainties was larger than 5mm in patients with greater fat thickness due to the baseline drift. CONCLUSIONS: The magnitude of the intrafractional motion was not uniform according to the direction, patients' physical characteristics, or tumour cavity location due to the baseline drift. Therefore, the intrafractional systematic movement should be properly managed.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Neoplasias de la Mama / Mecánica Respiratoria Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Radiother Oncol Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Neoplasias de la Mama / Mecánica Respiratoria Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Radiother Oncol Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Irlanda