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Structure of the full-length glucagon class B G-protein-coupled receptor.
Zhang, Haonan; Qiao, Anna; Yang, Dehua; Yang, Linlin; Dai, Antao; de Graaf, Chris; Reedtz-Runge, Steffen; Dharmarajan, Venkatasubramanian; Zhang, Hui; Han, Gye Won; Grant, Thomas D; Sierra, Raymond G; Weierstall, Uwe; Nelson, Garrett; Liu, Wei; Wu, Yanhong; Ma, Limin; Cai, Xiaoqing; Lin, Guangyao; Wu, Xiaoai; Geng, Zhi; Dong, Yuhui; Song, Gaojie; Griffin, Patrick R; Lau, Jesper; Cherezov, Vadim; Yang, Huaiyu; Hanson, Michael A; Stevens, Raymond C; Zhao, Qiang; Jiang, Hualiang; Wang, Ming-Wei; Wu, Beili.
Afiliación
  • Zhang H; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Qiao A; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Yang D; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Yang L; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Dai A; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • de Graaf C; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guo Shou Jing Road, Pudong, Shanghai 201203, China.
  • Reedtz-Runge S; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou 450001, China.
  • Dharmarajan V; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Zhang H; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guo Shou Jing Road, Pudong, Shanghai 201203, China.
  • Han GW; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands.
  • Grant TD; Novo Nordisk A/S, Novo Nordisk Park, Måløv 2760, Denmark.
  • Sierra RG; Department of Molecular Medicine, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, USA.
  • Weierstall U; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Nelson G; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Liu W; Department of Chemistry, Bridge Institute, University of Southern California, 3430 S. Vermont Avenue, Los Angeles, California 90089, USA.
  • Wu Y; Hauptman-Woodward Institute, SUNY at Buffalo, 700 Ellicott Street, Buffalo, New York 14203, USA.
  • Ma L; Linac Coherent Light Source (LCLS), SLAC National Accelerator Laboratory, Menlo Park, California 94025, USA.
  • Cai X; Department of Physics, Arizona State University, Tempe, Arizona 85287, USA.
  • Lin G; Department of Physics, Arizona State University, Tempe, Arizona 85287, USA.
  • Wu X; Biodesign Center for Applied Structural Discovery, Biodesign Institute, School of Molecular Sciences, Arizona State University, Tempe, Arizona 85287, USA.
  • Geng Z; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Dong Y; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Song G; School of Life Science and Technology, ShanghaiTech University, 393 Hua Xia Zhong Road, Pudong, Shanghai 201210, China.
  • Griffin PR; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Lau J; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Cherezov V; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guo Shou Jing Road, Pudong, Shanghai 201203, China.
  • Yang H; CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Pudong, Shanghai 201203, China.
  • Hanson MA; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Stevens RC; The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guo Shou Jing Road, Pudong, Shanghai 201203, China.
  • Zhao Q; School of Life Science and Technology, ShanghaiTech University, 393 Hua Xia Zhong Road, Pudong, Shanghai 201210, China.
  • Jiang H; Novo Nordisk Research Centre China, No. 20 Life Science Park Road, Changping District, Beijing 102206, China.
  • Wang MW; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
  • Wu B; Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
Nature ; 546(7657): 259-264, 2017 06 08.
Article en En | MEDLINE | ID: mdl-28514451

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Glucagón Límite: Humans Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Glucagón Límite: Humans Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido