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High-Intensity Focused Ultrasound Circular Cyclocoagulation in Glaucoma: A Step Forward for Cyclodestruction?
Mastropasqua, Rodolfo; Fasanella, Vincenzo; Mastropasqua, Alessandra; Ciancaglini, Marco; Agnifili, Luca.
Afiliación
  • Mastropasqua R; Moorfields Eye Hospital, London EC1V 2PD, UK.
  • Fasanella V; Ophthalmology Clinic, Department of Medicine and Ageing Science, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
  • Mastropasqua A; Ophthalmology Clinic, Department of Medicine and Ageing Science, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
  • Ciancaglini M; Ophthalmology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
  • Agnifili L; Ophthalmology Clinic, Department of Medicine and Ageing Science, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
J Ophthalmol ; 2017: 7136275, 2017.
Article en En | MEDLINE | ID: mdl-28512580
The ciliary body ablation is still considered as a last resort treatment to reduce the intraocular pressure (IOP) in uncontrolled glaucoma. Several ablation techniques have been proposed over the years, all presenting a high rate of complications, nonselectivity for the target organ, and unpredictable dose-effect relationship. These drawbacks limited the application of cyclodestructive procedures almost exclusively to refractory glaucoma. High-intensity focused ultrasound (HIFU), proposed in the early 1980s and later abandoned because of the complexity and side effects of the procedure, was recently reconsidered in a new approach to destroy the ciliary body. Ultrasound circular cyclocoagulation (UC3), by using miniaturized transducers embedded in a dedicated circular-shaped device, permits to selectively treat the ciliary body in a one-step, computer-assisted, and non-operator-dependent procedure. UC3 shows a high level of safety along with a predictable and sustained IOP reduction in patients with refractory glaucoma. Because of this, the indication of UC3 was recently extended also to naïve-to-surgery patients, thus reconsidering the role and timing of ciliary body ablation in the surgical management of glaucoma. This article provides a review of the most used cycloablative techniques with particular attention to UC3, summarizing the current knowledge about this procedure and future possible developments.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Ophthalmol Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Ophthalmol Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos