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Dose tracking assessment for image-guided radiotherapy of the prostate bed and the impact on clinical workflow.
Orlandini, Lucia Clara; Coppola, Marianna; Fulcheri, Christian; Cernusco, Luna; Wang, Pei; Cionini, Luca.
Afiliación
  • Orlandini LC; Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023, Florence, Italy.
  • Coppola M; Department of Radiation Oncology, Sichuan Cancer Hospital, No.55, the 4th Section, Renmin South Road, Chengdu, China.
  • Fulcheri C; Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023, Florence, Italy.
  • Cernusco L; Azienda Ospedaliera di Perugia, Health Physics Department, Piazzale Menghini 1, 06129, Perugia, Italy.
  • Wang P; Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023, Florence, Italy.
  • Cionini L; Department of Radiation Oncology, Sichuan Cancer Hospital, No.55, the 4th Section, Renmin South Road, Chengdu, China. dengwangpei@163.com.
Radiat Oncol ; 12(1): 78, 2017 Apr 28.
Article en En | MEDLINE | ID: mdl-28454559
BACKGROUND: The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding dose tracking to the routine workflow for radiotherapy. METHODS: Daily cone beam computed tomography was conducted for image-guided radiotherapy, and weekly cumulative delivered doses were calculated for dose tracking. Deformable image registration was applied to map weekly dose distributions to the original treatment plan and to create a cumulative dose distribution. The dose-volume histogram (DVH) cut-off points for the rectum and bladder and the planning target volume (PTV), were used to compare the planned and cumulative delivered doses. The additional time required by the departmental staff to complete these duties was recorded. RESULTS: The PTV coverage of the delivered treatment did not satisfy the expected goal for three patients (V98% >98%). In another three patients, the DVH cut-off point for the bladder was higher than the limits, while for the rectum, treatment was as expected in all cases (two patients failed both their bladder constraints and the PTV coverage). Overall, four patients did not satisfy one or more criteria at the end of their treatment. CONCLUSIONS: A well-defined strategy for dose tracking assessment is feasible, would have minimal impact on the workload of a radiotherapy department, and may offer objective information to support radiation oncologists in making decisions about adaptive procedures.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Planificación de la Radioterapia Asistida por Computador / Tomografía Computarizada por Rayos X / Flujo de Trabajo / Órganos en Riesgo / Radioterapia Guiada por Imagen Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Radiat Oncol Asunto de la revista: NEOPLASIAS / RADIOTERAPIA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Planificación de la Radioterapia Asistida por Computador / Tomografía Computarizada por Rayos X / Flujo de Trabajo / Órganos en Riesgo / Radioterapia Guiada por Imagen Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Radiat Oncol Asunto de la revista: NEOPLASIAS / RADIOTERAPIA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido