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Central line-associated blood stream infections: characteristics and risk factors for mortality over a 5.5-year period.
Atilla, Aynur; Doganay, Zahide; Kefeli Çelik, Hale; Demirag, Mehmet Derya; S Kiliç, Sirri.
Afiliación
  • Atilla A; Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, Turkey.
  • Doganay Z; Department of Anesthesiology and Reanimation, Samsun Training and Research Hospital, Samsun, Turkey.
  • Kefeli Çelik H; Department of Anesthesiology and Reanimation, Samsun Training and Research Hospital, Samsun, Turkey.
  • Demirag MD; Department of Internal Medicine, Samsun Training and Research Hospital, Samsun, Turkey.
  • S Kiliç S; Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, Turkey.
Turk J Med Sci ; 47(2): 646-652, 2017 Apr 18.
Article en En | MEDLINE | ID: mdl-28425261
BACKGROUND/AIM: Central line-associated bloodstream infections (CLABSIs) are associated with substantial morbidity and mortality and the infection rates vary in a wide range1397645907(high: 62.5%; low: 20%) in developing countries. We aimed to investigate the characteristics and the risk factors for mortality in patients with CLABSIs in intensive care units (ICUs) and provide the relevant data. MATERIALS AND METHODS: The electronic medical records database and file records obtained through active surveillance by an infection control committee of a hospital were screened to identify patients with CLABSIs hospitalized from January 2008 through July 2013. RESULTS: A total of 166 CLABSI episodes in 158 patients out of 17,553 on 38,562 catheter and 94,512 hospitalization days were evaluated. The infection developed in catheterized patients at a median of 14 days (range 2-88), and the highest infection rate with 13.4% (n = 20) was the femoral region among the places where the catheter was inserted. Of the patients catheterized, 54.4% survived whereas 45.6% died. In patients having Candida infection, the mortality was significantly higher. High APACHE II scores and Candida infections were found to be significant risk factors associated with mortality. CONCLUSION: APACHE II scores and bloodstream infection with Candida species were the most powerful predictors of mortality. In ICU practice, health-care givers must consider the emerging role of Candida for both invasiveness and mortality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cateterismo Venoso Central / Infección Hospitalaria / Bacteriemia / Infecciones Relacionadas con Catéteres Tipo de estudio: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Turk J Med Sci Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Turquía
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cateterismo Venoso Central / Infección Hospitalaria / Bacteriemia / Infecciones Relacionadas con Catéteres Tipo de estudio: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Turk J Med Sci Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Turquía