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In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3).
Dervis, Emine; Yurt Kilcar, Ayfer; Medine, Emin Ilker; Tekin, Volkan; Cetkin, Buse; Uygur, Emre; Muftuler, Fazilet Zumrut Biber.
Afiliación
  • Dervis E; 1 Department of Nuclear Applications, Institute of Nuclear Science, Ege University , Izmir, Turkey .
  • Yurt Kilcar A; 2 Department of Chemistry, Faculty of Science, Ege University , Izmir, Turkey .
  • Medine EI; 1 Department of Nuclear Applications, Institute of Nuclear Science, Ege University , Izmir, Turkey .
  • Tekin V; 1 Department of Nuclear Applications, Institute of Nuclear Science, Ege University , Izmir, Turkey .
  • Cetkin B; 1 Department of Nuclear Applications, Institute of Nuclear Science, Ege University , Izmir, Turkey .
  • Uygur E; 1 Department of Nuclear Applications, Institute of Nuclear Science, Ege University , Izmir, Turkey .
  • Muftuler FZB; 2 Department of Chemistry, Faculty of Science, Ege University , Izmir, Turkey .
Cancer Biother Radiopharm ; 32(3): 75-81, 2017 Apr.
Article en En | MEDLINE | ID: mdl-28358602
Recently, the synthesis of radiolabeled plant origin compounds has been increased due to their high uptake on some cancer cell lines. Eugenol (EUG), a phenolic natural compound in the essential oils of different spices such as Syzygium aromaticum (clove), Pimenta racemosa (bay leaves), and Cinnamomum verum (cinnamon leaf), has been exploited for various medicinal applications. EUG has antiviral, antioxidant, and anti-inflammatory functions and several anticancer properties. The objective of this article is to synthesize radioiodinated (131I) EUG and investigate its effect on Caco2, MCF7, and PC3 adenocarcinoma cell lines. It is observed that radioiodinated EUG would have potential on therapy and imaging due to its notable uptakes in studied cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eugenol / Adenocarcinoma / Radiofármacos / Radioisótopos de Yodo Límite: Humans Idioma: En Revista: Cancer Biother Radiopharm Asunto de la revista: FARMACIA / FARMACOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Eugenol / Adenocarcinoma / Radiofármacos / Radioisótopos de Yodo Límite: Humans Idioma: En Revista: Cancer Biother Radiopharm Asunto de la revista: FARMACIA / FARMACOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2017 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos