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High-content screen using zebrafish (Danio rerio) embryos identifies a novel kinase activator and inhibitor.
Geldenhuys, Werner J; Bergeron, Sadie A; Mullins, Jackie E; Aljammal, Rowaa; Gaasch, Briah L; Chen, Wei-Chi; Yun, June; Hazlehurst, Lori A.
Afiliación
  • Geldenhuys WJ; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, United States. Electronic address: werner.geldenhuys@hsc.wvu.edu.
  • Bergeron SA; Department of Biology, Eberly College of Arts and Sciences, West Virginia University, Morgantown, WV 26506, United States.
  • Mullins JE; Department of Biology, Eberly College of Arts and Sciences, West Virginia University, Morgantown, WV 26506, United States.
  • Aljammal R; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, United States.
  • Gaasch BL; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, United States.
  • Chen WC; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, United States.
  • Yun J; Department of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, United States.
  • Hazlehurst LA; Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506, United States.
Bioorg Med Chem Lett ; 27(9): 2029-2037, 2017 05 01.
Article en En | MEDLINE | ID: mdl-28320616
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Activadores de Enzimas / Inhibidores de Proteínas Quinasas / Embrión no Mamífero / Descubrimiento de Drogas Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Activadores de Enzimas / Inhibidores de Proteínas Quinasas / Embrión no Mamífero / Descubrimiento de Drogas Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido