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Letter to the Editor: Can dog allergen immunotherapy reduce concomitant allergic sensitization to other furry animals? A preliminary experience.
Liccardi, G; Calzetta, L; Salzillo, A; Billeri, L; Lucà, G; Rogliani, P.
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  • Liccardi G; Department of Pulmonology, Haematology and Oncology, Division of Pulmonology and Allergology, High Speciality "A. Cardarelli" Hospital, Naples, Italy. Postgraduate School of Respiratory Medicine, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy. Phone: +39 081 747 3335-6
  • Calzetta L; Postgraduate School of Respiratory Medicine, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy. Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
  • Salzillo A; Department of Pulmonology, Haematology and Oncology, Division of Pulmonology and Allergology, High Speciality "A. Cardarelli" Hospital, Naples, Italy.
  • Billeri L; Department of Laboratory Medicine, University Hospital Padova, Italy.
  • Lucà G; Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
  • Rogliani P; Postgraduate School of Respiratory Medicine, Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy. Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
Eur Ann Allergy Clin Immunol ; 49(2): 92-96, 2017 03.
Article en En | MEDLINE | ID: mdl-28294591
Summary: It has been shown that allergen immunotherapy (AIT) is effective in reducing symptoms of allergic asthma and rhinitis. Data on the efficacy are less convincing with regard to AIT for allergens of common pets (cats/dogs). We describe a case of dog allergy in which we explored if dog AIT (DAI) could reduce a concomitant allergic sensitization to other allergens of furry animals. Our case demonstrates the efficacy of sublingual DAI on SPTs, symptom score, and spirometric responses despite persistent exposure to dog allergens at home in a patient sensitized, but not exposed, to several other furry animals. Moreover, this is the first report suggesting that DAI is able to reduce SPTs responses not only to dog, but also to other furry animals such as rabbit, horse, mouse, rat, hamster, cow. We recommend an accurate anamnesis and diagnosis of dog allergy before prescribing DAI. In particular, the use of ImmunoCAP ISAC is essential to verify the presence of IgE to lipocalins / albumins belonging to other furry animals. Obviously further studies carried out by using different DAI schedules, allergen amount and time of re-evaluation, laboratory procedure should be performed to confirm our findings.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Alérgenos / Perros / Inmunoterapia Sublingual / Cabello Tipo de estudio: Diagnostic_studies Límite: Adult / Animals / Humans / Male Idioma: En Revista: Eur Ann Allergy Clin Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Italia
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Alérgenos / Perros / Inmunoterapia Sublingual / Cabello Tipo de estudio: Diagnostic_studies Límite: Adult / Animals / Humans / Male Idioma: En Revista: Eur Ann Allergy Clin Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Italia