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Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives.
Zhu, Gao-Xiang; Cheng, Pi-Le; Goto, Masuo; Zhang, Na; Morris-Natschke, Susan L; Hsieh, Kan-Yen; Yang, Guan-Zhou; Yang, Qian-Ru; Liu, Ying-Qian; Chen, Hai-Le; Zhang, Xiao-Shuai; Lee, Kuo-Hsiung.
Afiliación
  • Zhu GX; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Cheng PL; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Goto M; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States.
  • Zhang N; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Morris-Natschke SL; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States.
  • Hsieh KY; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States.
  • Yang GZ; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Yang QR; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Liu YQ; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China. Electronic address: yqliu@lzu.edu.cn.
  • Chen HL; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Zhang XS; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Lee KH; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, United States; Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan. Electronic address: khlee@email.unc.edu.
Bioorg Med Chem Lett ; 27(8): 1750-1753, 2017 04 15.
Article en En | MEDLINE | ID: mdl-28285912

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Camptotecina / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperazinas / Camptotecina / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido