Your browser doesn't support javascript.
loading
Bottom-up or top-down: unit cost estimation of tuberculosis diagnostic tests in India.
Rupert, S; Vassall, A; Raizada, N; Khaparde, S D; Boehme, C; Salhotra, V S; Sachdeva, K S; Nair, S A; Hoog, A H Van't.
Afiliación
  • Rupert S; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
  • Vassall A; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands, Social and Mathematical Epidemiology Group, Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
  • Raizada N; Foundation for Innovative New Diagnostics, New Delhi.
  • Khaparde SD; Central TB Division, Government of India, New Delhi.
  • Boehme C; Foundation for Innovative New Diagnostics, New Delhi.
  • Salhotra VS; Central TB Division, Ministry of Health and Family Welfare, New Delhi.
  • Sachdeva KS; Central TB Division, Government of India, New Delhi.
  • Nair SA; World Health Organization, Country Office for India, New Delhi, India.
  • Hoog AH; Academic Medical Centre, University of Amsterdam, Department of Global Health, Amsterdam, The Netherlands.
Int J Tuberc Lung Dis ; 21(4): 375-380, 2017 04 01.
Article en En | MEDLINE | ID: mdl-28284251
SETTING: Of 18 sites that participated in an implementation study of the Xpert® MTB/RIF assay in India, we selected five microscopy centres and two reference laboratories. OBJECTIVE: To obtain unit costs of diagnostic tests for tuberculosis (TB) and drug-resistant TB. DESIGN: Laboratories were purposely selected to capture regional variations and different laboratory types. Both bottom-up and the top-down methods were used to estimate unit costs. RESULTS: At the microscopy centres, mean bottom-up unit costs were respectively US$0.83 (range US$0.60-US$1.10) and US$12.29 (US$11.61-US$12.89) for sputum smear microscopy and Xpert. At the reference laboratories, mean unit costs were US$1.69 for the decontamination procedure, US$9.83 for a solid culture, US$11.06 for a liquid culture, US$29.88 for a drug susceptibility test, and US$18.18 for a line-probe assay. Top-down mean unit cost estimates were higher for all tests, and for sputum smear microscopy and Xpert these increased to respectively US$1.51 and US$13.58. The difference between bottom-up and top-down estimates was greatest for tests performed at the reference laboratories. CONCLUSION: These unit costs for TB diagnostics can be used to estimate resource requirements and cost-effectiveness in India, taking into account geographical location, laboratory type and capacity utilisation.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Reacción en Cadena de la Polimerasa / Tuberculosis Resistente a Múltiples Medicamentos / Microscopía Tipo de estudio: Clinical_trials / Diagnostic_studies / Health_economic_evaluation Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Int J Tuberc Lung Dis Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Francia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Reacción en Cadena de la Polimerasa / Tuberculosis Resistente a Múltiples Medicamentos / Microscopía Tipo de estudio: Clinical_trials / Diagnostic_studies / Health_economic_evaluation Límite: Humans País/Región como asunto: Asia Idioma: En Revista: Int J Tuberc Lung Dis Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Francia