Magnetism-assisted modification of screen printed electrode with magnetic multi-walled carbon nanotubes for electrochemical determination of dopamine.
Mater Sci Eng C Mater Biol Appl
; 74: 62-69, 2017 May 01.
Article
en En
| MEDLINE
| ID: mdl-28254335
A simple and sensitive dopamine (DA) electrochemical sensor was fabricated based on magnetism-assisted modification of screen printed electrode (SPE) with magnetic multi-walled carbon nanotubes (mMWCNTs). The mMWCNTs modified electrodes (mMWCNTs/SPE) combines the advantages of SPE and the simultaneous contribution of magnetic nanoparticles (MNPs) and MWCNTs, increasing sensitivity and selectivity of DA detection. The linearity was found between 5µM to 180µM, with the limit of detection (LOD) of 0.43µM. In the mean time, this modified electrode exhibited excellent selectivity for DA detection with almost no interference from ascorbic acid (AA), which co-exists with DA in many bio-samples and causes common interference. Finally, this novel electrode has been applied to determine DA concentration in spiked human blood serum and satisfactory recovery was found in the range of 97.43-102.94% with the RSDs of less than 2.27%. This work developed a sensitive and reliable electrochemical analytical method based on mMWCNTs/SPE, which exhibits great potential for diagnosis of the diseases related to DA.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dopamina
/
Técnicas Electroquímicas
/
Nanopartículas de Magnetita
Límite:
Humans
Idioma:
En
Revista:
Mater Sci Eng C Mater Biol Appl
Año:
2017
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Países Bajos