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Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.
Wigger, Leonore; Cruciani-Guglielmacci, Céline; Nicolas, Anthony; Denom, Jessica; Fernandez, Neïké; Fumeron, Frédéric; Marques-Vidal, Pedro; Ktorza, Alain; Kramer, Werner; Schulte, Anke; Le Stunff, Hervé; Liechti, Robin; Xenarios, Ioannis; Vollenweider, Peter; Waeber, Gérard; Uphues, Ingo; Roussel, Ronan; Magnan, Christophe; Ibberson, Mark; Thorens, Bernard.
Afiliación
  • Wigger L; Vital-IT Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
  • Cruciani-Guglielmacci C; Unité de Biologie Fonctionnelle et Adaptative (BFA), CNRS UMR 8251, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France.
  • Nicolas A; INSERM, Sorbonne Paris Cité, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; UPMC, Sorbonne Universités, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Centre de Recherche des Cordeliers (CRC), UMR_
  • Denom J; Unité de Biologie Fonctionnelle et Adaptative (BFA), CNRS UMR 8251, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France.
  • Fernandez N; Unité de Biologie Fonctionnelle et Adaptative (BFA), CNRS UMR 8251, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France.
  • Fumeron F; INSERM, Sorbonne Paris Cité, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; UPMC, Sorbonne Universités, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Centre de Recherche des Cordeliers (CRC), UMR_
  • Marques-Vidal P; Department of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
  • Ktorza A; Recherche de Découverte, PIT Métabolisme, Institut de Recherche Servier (IdRS), 92150 Suresnes, France.
  • Kramer W; Biomedical and Scientific Consulting, 55130 Mainz, Germany.
  • Schulte A; Diabetes Research, Islet Biology Cluster, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, 65926 Frankfurt am Main, Germany.
  • Le Stunff H; Unité de Biologie Fonctionnelle et Adaptative (BFA), CNRS UMR 8251, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France; Institut de biologie intégrative de la cellule (I2BC), CNRS UMR 9198, Université Paris-Sud, Université Paris-Saclay, 91190 Gif-sur-Yvette, France.
  • Liechti R; Vital-IT Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
  • Xenarios I; Vital-IT Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
  • Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
  • Waeber G; Department of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
  • Uphues I; Cardiometabolic Diseases Research, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400 Biberach (Riss), Germany.
  • Roussel R; INSERM, Sorbonne Paris Cité, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; UPMC, Sorbonne Universités, Centre de Recherce des Cordeliers (CRC), UMR_S 1138, 75006 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Centre de Recherche des Cordeliers (CRC), UMR_
  • Magnan C; Unité de Biologie Fonctionnelle et Adaptative (BFA), CNRS UMR 8251, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris, France.
  • Ibberson M; Vital-IT Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland. Electronic address: mark.ibberson@sib.swiss.
  • Thorens B; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland. Electronic address: bernard.thorens@unil.ch.
Cell Rep ; 18(9): 2269-2279, 2017 02 28.
Article en En | MEDLINE | ID: mdl-28249170
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Ceramidas / Diabetes Mellitus Tipo 2 / Susceptibilidad a Enfermedades Tipo de estudio: Observational_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Ceramidas / Diabetes Mellitus Tipo 2 / Susceptibilidad a Enfermedades Tipo de estudio: Observational_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos