Elimination of indigenous linear plasmids in Streptomyces hygroscopicus var. jinggangensis and Streptomyces sp. FR008 to increase validamycin A and candicidin productivities.

Lu, Chenyang; Wu, Hang; Su, Xiurong; Bai, Linquan

Lu, Chenyang; Wu, Hang; Su, Xiurong; Bai, Linquan.

Afiliación

Lu C; School of Marine Sciences, Ningbo University, 818 Fenghua Road, Ningbo City, Zhejiang Province, 315211, People's Republic of China.
Wu H; State Key Laboratory of Microbial Metabolism and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China.
Su X; Joint International Research Laboratory of Metabolic and Developmental Sciences, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
Bai L; Institute of Health Sciences, School of Life Sciences, Anhui University, Hefei City, Anhui Province, 230039, People's Republic of China.

Appl Microbiol Biotechnol ; 101(10): 4247-4257, 2017 May.

Article en En | MEDLINE | ID: mdl-28238083

Asunto(s)

Candicidina/biosíntesis; Inositol/análogos & derivados; Plásmidos; Metabolismo Secundario/genética; Streptomyces/genética; Proteínas Bacterianas/genética; Regulación Bacteriana de la Expresión Génica; Prueba de Complementación Genética; Inositol/biosíntesis; Familia de Multigenes; Mutación; Regiones Promotoras Genéticas; Streptomyces/metabolismo

Palabras clave

Elimination; Indigenous linear plasmid; Overproduction; Validamycin A

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plásmidos / Streptomyces / Candicidina / Metabolismo Secundario / Inositol Idioma: En Revista: Appl Microbiol Biotechnol Año: 2017 Tipo del documento: Article Pais de publicación: Alemania

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