Your browser doesn't support javascript.
loading
Remotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis.
Charvet, Leigh; Shaw, Michael; Dobbs, Bryan; Frontario, Ariana; Sherman, Kathleen; Bikson, Marom; Datta, Abhishek; Krupp, Lauren; Zeinapour, Esmail; Kasschau, Margaret.
Afiliación
  • Charvet L; Department of Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Shaw M; Department of Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Dobbs B; Department of Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Frontario A; Lake Erie College of Osteopathic Medicine, Erie, PA, USA.
  • Sherman K; Department of Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Bikson M; Engineering Department, City College of New York, New York, NY, USA.
  • Datta A; Soterix Medical, New York, NY, USA.
  • Krupp L; Department of Neurology, New York University Langone Medical Center, New York, NY, USA.
  • Zeinapour E; Engineering Department, City College of New York, New York, NY, USA.
  • Kasschau M; School of Health Technology and Management, Stony Brook Medicine, Stony Brook, NY, USA.
Neuromodulation ; 21(4): 383-389, 2018 Jun.
Article en En | MEDLINE | ID: mdl-28225155
OBJECTIVE: To explore the efficacy of remotely-supervised transcranial direct current stimulation (RS-tDCS) paired with cognitive training (CT) exercise in participants with multiple sclerosis (MS). METHODS: In a feasibility study of RS-tDCS in MS, participants completed ten sessions of tDCS paired with CT (1.5 mA × 20 min, dorsolateral prefrontal cortex montage). RS-tDCS participants were compared to a control group of adults with MS who underwent ten 20-min CT sessions through the same remotely supervised procedures. Cognitive outcomes were tested by composite scores measuring change in performance on standard tests (Brief International Cognitive Assessment in MS or BICAMS), basic attention (ANT-I Orienting and Attention Networks, Cogstate Detection), complex attention (ANT-I Executive Network, Cogstate Identification and One-Back), and intra-individual response variability (ANT-I and Cogstate identification; sensitive markers of disease status). RESULTS: After ten sessions, the tDCS group (n = 25) compared to the CT only group (n = 20) had significantly greater improvement in complex attention (p = 0.01) and response variability (p = 0.01) composites. The groups did not differ in measures of basic attention (p = 0.95) or standard cognitive measures (p = 0.99). CONCLUSIONS: These initial findings indicate benefit for RS-tDCS paired with CT in MS. Exploratory analyses indicate that the earliest tDCS cognitive benefit is seen in complex attention and response variability. Telerehabilitation using RS-tDCS combined with CT may lead to improved outcomes in MS.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Estimulación Transcraneal de Corriente Directa / Esclerosis Múltiple Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neuromodulation Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos del Conocimiento / Estimulación Transcraneal de Corriente Directa / Esclerosis Múltiple Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neuromodulation Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos