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Immunotoxin: A new tool for cancer therapy.
Allahyari, Hossein; Heidari, Sahar; Ghamgosha, Mehdi; Saffarian, Parvaneh; Amani, Jafar.
Afiliación
  • Allahyari H; 1 Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Heidari S; 1 Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Ghamgosha M; 1 Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
  • Saffarian P; 2 Department of Microbiology, Tehran Medical Branch, Islamic Azad University, Tehran, Iran.
  • Amani J; 3 Applied Microbiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Tumour Biol ; 39(2): 1010428317692226, 2017 Feb.
Article en En | MEDLINE | ID: mdl-28218037
Cancer is one of the main reasons of death in the most countries and in Iran. Immunotherapy quickly became one of the best methods of cancer treatment, along with chemotherapy and radiation. "Immunotoxin Therapy" is a promising way of cancer therapy that is mentioned in this field. Immunotoxins are made from a toxin attaching to an antibody target proteins present on cancer cells. The first-generation immunotoxins were made of a full-length toxin attached to whole monoclonal antibodies. But, these immunotoxins could bind to normal cells. DAB389IL2 was the first immunotoxin approved by the Food and Drug Administration. Current trends and researches are ongoing on finding proteins that in combination with immunotoxins have minimal immunogenicity and the most potency for target cell killing.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunotoxinas / Neoplasias Límite: Animals / Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunotoxinas / Neoplasias Límite: Animals / Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Países Bajos