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Pulmonary nodules in African migrants caused by chronic schistosomiasis.
Gobbi, Federico; Buonfrate, Dora; Angheben, Andrea; Beltrame, Anna; Bassetti, Matteo; Bertolaccini, Luca; Bogina, Giuseppe; Caia, Simone; Duranti, Silvia; Gobbo, Maria; Marchese, Valentina; Marocco, Stefania; Merelli, Maria; Monteiro, Geraldo; Terzi, Alberto; Bisoffi, Zeno.
Afiliación
  • Gobbi F; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy; Global Health Center, Florence, Italy.
  • Buonfrate D; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy. Electronic address: dora.buonfrate@sacrocuore.it.
  • Angheben A; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Beltrame A; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Bassetti M; Clinic of Infectious Disease University Hospital "Santa Maria della Misericordia", Udine, Italy.
  • Bertolaccini L; Thoracic Surgery Unit, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Bogina G; Pathology Unit, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Caia S; Department of Radiology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Duranti S; Clinic of Infectious Disease University Hospital "Santa Maria della Misericordia", Udine, Italy.
  • Gobbo M; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Marchese V; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Marocco S; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Merelli M; Clinic of Infectious Disease University Hospital "Santa Maria della Misericordia", Udine, Italy.
  • Monteiro G; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Terzi A; Thoracic Surgery Unit, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
  • Bisoffi Z; Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy; Global Health Center, Florence, Italy.
Lancet Infect Dis ; 17(5): e159-e165, 2017 05.
Article en En | MEDLINE | ID: mdl-28214126
Schistosomiasis is a neglected tropical disease that can cause mainly hepatic and genitourinary damage, depending on the species. Involvement of the lungs has been commonly described in acute infection (Katayama syndrome) and chronic infection (pulmonary hypertension). Although rarely reported in the scientific literature, cases of lung nodules due to chronic schistosome infection are also possible and are probably more frequent than commonly thought. Here we report seven cases of African migrants who were diagnosed with chronic schistosomiasis and pulmonary nodules due to deposition of schistosome eggs, and we compare our findings to the case reports found in the scientific literature. We discuss the management of these patients in a non-endemic setting, beginning with a first fundamental step that is to include parasitic infections, namely schistosomiasis, in the differential diagnosis of pulmonary nodules in African immigrants. All patients responded to antiparasitic treatment with praziquantel after a relatively short time. We therefore conclude that lung biopsies and other invasive procedures (performed in the first cases to rule out other potential causes, such as tuberculosis or malignant nodules) can be avoided or postponed.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Praziquantel / Migrantes / Esquistosomiasis Urinaria Límite: Adolescent / Adult / Animals / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Praziquantel / Migrantes / Esquistosomiasis Urinaria Límite: Adolescent / Adult / Animals / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos