Antimicrobial and antioxidant activities of Flammulina velutipes polysaccharides and polysaccharide-iron(III) complex [corrected].
Carbohydr Polym
; 161: 26-32, 2017 04 01.
Article
en En
| MEDLINE
| ID: mdl-28189237
FVP is polysacchrides obtained from Flammulina velutipes. A polysacchride named FVP2 was isolated from FVP by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography. FVP-Fe and FVP2-Fe were synthesized by neutralization of FeCl3 carbohydrate solution. The antibacterial and antifungal activities of FVP, FVP2, FVP-Fe, FVP2-Fe were investigated and their antioxidant effects on hydroxyl, 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion, 2,2'-azobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, reducing power, inhibition of malondialdehyde (MDA) were assessed in vitro. The results suggested that FVP-Fe and FVP2-Fe significantly suppressed the growth of bacteria Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, and have relatively strong antioxidant activity to scavenge superoxide anion radical. In addition, FVP exhibited strong antioxidant activity to eliminate hydroxyl, DPPH, ABTS radicals, had high reducing power and inhibited the MDA production of health mice liver homogenate induced by auto-oxidation and Fe2+-H2O2 system.
Palabras clave
2,2'-Azobis(3-ethylbenzothiazoline-6-sulfonic acid) (PubChem CID: 73857778; Antimicrobial activity; Antioxidant activity; DPPH, Free radical (PubChem CID: 2735032); Flammulina velutipes polysaccharides; Hydroxyl (PubChem CID: 961); Iron chloride (FeCl(3)) (PubChem CID: 24380); Malondialdehyde (PubChem CID: 10964); Polysacchride-iron (III) complex; Superoxide anion (PubChem CID: 5359597)
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polisacáridos
/
Bacterias
/
Compuestos Férricos
/
Flammulina
Límite:
Animals
Idioma:
En
Revista:
Carbohydr Polym
Año:
2017
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Reino Unido