Reduced mitochondrial activity in colonocytes facilitates AMPK&#945;2-dependent inflammation.

Heller, Sandra; Penrose, Harrison M; Cable, Chloe; Biswas, Debjani; Nakhoul, Hani; Baddoo, Melody; Flemington, Erik; Crawford, Susan E; Savkovic, Suzana D

Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation.

Heller, Sandra; Penrose, Harrison M; Cable, Chloe; Biswas, Debjani; Nakhoul, Hani; Baddoo, Melody; Flemington, Erik; Crawford, Susan E; Savkovic, Suzana D.

Afiliación

Heller S; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Penrose HM; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Cable C; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Biswas D; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Nakhoul H; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Baddoo M; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Flemington E; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA.
Crawford SE; Department of Surgery, NorthShore Research Institute, University of Chicago Pritzker School of Medicine, Evanston, Illinois, USA.
Savkovic SD; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, Louisiana, USA; ssavkovi@tulane.edu.

FASEB J ; 31(5): 2013-2025, 2017 05.

Article en En | MEDLINE | ID: mdl-28183804

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Linfocitos B/metabolismo; Inflamación/metabolismo; Mitocondrias/metabolismo; Animales; Femenino; Humanos; Ratones Endogámicos C57BL; Mitocondrias/efectos de los fármacos; FN-kappa B/metabolismo; Regiones Promotoras Genéticas/genética; Transducción de Señal/fisiología; Factor de Necrosis Tumoral alfa/metabolismo; Factor de Necrosis Tumoral alfa/farmacología

Palabras clave

RNA-seq; inflammatory bowel disease; intestine; ρ0 cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos B / Proteínas Quinasas Activadas por AMP / Inflamación / Mitocondrias Límite: Animals / Female / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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