In vitro activities of several new macrolide antibiotics against Mycobacterium avium complex.
Antimicrob Agents Chemother
; 33(9): 1614-6, 1989 Sep.
Article
en En
| MEDLINE
| ID: mdl-2817858
The in vitro activities of 12 macrolide compounds against 28 Mycobacterium avium complex strains isolated from patients with acquired immunodeficiency syndrome were determined by the conventional proportion method and by the BACTEC method. Clarithromycin (A-56268; TE-031), a new macrolide compound, was the most active agent tested, inhibiting 90% of strains at an MIC of 4 micrograms/ml by the BACTEC method. Roxithromycin (RU 28965) and erythromycylamine inhibited 90% of strains at 16 micrograms/ml. The organisms showed high levels of resistance to most other macrolide compounds.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complejo Mycobacterium avium
/
Antibacterianos
Límite:
Humans
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Estados Unidos