Your browser doesn't support javascript.
loading
Cannabis use and symptom severity in individuals at ultra high risk for psychosis: a meta-analysis.
Carney, R; Cotter, J; Firth, J; Bradshaw, T; Yung, A R.
Afiliación
  • Carney R; Division of Psychology and Mental Health, University of Manchester, Manchester, UK.
  • Cotter J; Division of Psychology and Mental Health, University of Manchester, Manchester, UK.
  • Firth J; Division of Psychology and Mental Health, University of Manchester, Manchester, UK.
  • Bradshaw T; Division of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK.
  • Yung AR; Division of Psychology and Mental Health, University of Manchester, Manchester, UK.
Acta Psychiatr Scand ; 136(1): 5-15, 2017 07.
Article en En | MEDLINE | ID: mdl-28168698
OBJECTIVE: We aimed to assess whether individuals at ultra high risk (UHR) for psychosis have higher rates of cannabis use and cannabis use disorders (CUDs) than non-UHR individuals and determine whether UHR cannabis users have more severe psychotic experiences than non-users. METHOD: We conducted a meta-analysis of studies reporting cannabis use in the UHR group and/or positive or negative symptoms among UHR cannabis users and non-users. Logit event rates were calculated for cannabis use, in addition to odds ratios to assess the difference between UHR and controls. Severity of clinical symptoms in UHR cannabis users and non-users was compared using Hedges' g. RESULTS: Thirty unique studies were included (UHR n = 4205, controls n = 667) containing data from cross-sectional and longitudinal studies, and randomised control trials. UHR individuals have high rates of current (26.7%) and lifetime (52.8%) cannabis use, and CUDs (12.8%). Lifetime use and CUDs were significantly higher than controls (lifetime OR: 2.09; CUD OR: 5.49). UHR cannabis users had higher rates of unusual thought content and suspiciousness than non-users. CONCLUSION: Ultra high risk individuals have high rates of cannabis use and CUDs, and cannabis users had more severe positive symptoms. Targeting substance use during the UHR phase may have significant benefits to an individual's long-term outcome.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Abuso de Marihuana / Uso de la Marihuana Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Adult / Female / Humans / Male Idioma: En Revista: Acta Psychiatr Scand Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Abuso de Marihuana / Uso de la Marihuana Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Límite: Adult / Female / Humans / Male Idioma: En Revista: Acta Psychiatr Scand Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos