[Study of the effects of calcium antagonists on respiration mechanics in patients with occlusive ventilation impairment]. / Badania wplywu antagonistów wapnia na mechanike oddychania u chorych z obturacyjnym uposledzeniem wentylacji.
Wiad Lek
; 42(5): 278-83, 1989 Mar 01.
Article
en Pl
| MEDLINE
| ID: mdl-2815744
In 113 patients and 33 controls the bronchodilating effect of three most frequently used calcium channel blockers nifedipine, verapamil and diltiazem was studied. The group comprised 76 men and 41 women aged 20 to 60 years, with bronchospastic conditions of various aetiology. The Jaeger Bodytest apparatus was used. The indices of bronchial patency determined in the study were: FEV1, MEF50, and Rt before and 30 and 120 minutes after one dose of nifedipine 20 mg, verapamil 80 mg and diltiazem 120 mg in various subgroups of patients. The criteria of bronchospasm reversibility were those accepted by SEPCR. It was shown that oral administration of one mean dose of calcium channel blocker causes improvement of the indices of bronchial patency in about one-third of cases contrary to the results in controls. The bronchodilating effect was greatest after nifedipine. The obtained results justify the trials of treatment with calcium channel antagonists in cases with reversible bronchospasm of various aetiology.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espasmo Bronquial
/
Bloqueadores de los Canales de Calcio
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Pl
Revista:
Wiad Lek
Asunto de la revista:
MEDICINA
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Polonia