Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-<i>&#954;</i>B signaling by degrading TRAF2-associated cIAP1 in cancer cells.

Mitsuuchi, Y; Benetatos, C A; Deng, Y; Haimowitz, T; Beck, S C; Arnone, M R; Kapoor, G S; Seipel, M E; Chunduru, S K; McKinlay, M A; Begley, C G; Condon, S M

Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-κB signaling by degrading TRAF2-associated cIAP1 in cancer cells.

Mitsuuchi, Y; Benetatos, C A; Deng, Y; Haimowitz, T; Beck, S C; Arnone, M R; Kapoor, G S; Seipel, M E; Chunduru, S K; McKinlay, M A; Begley, C G; Condon, S M.

Afiliación

Mitsuuchi Y; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Benetatos CA; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Deng Y; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Haimowitz T; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Beck SC; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Arnone MR; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Kapoor GS; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Seipel ME; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Chunduru SK; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
McKinlay MA; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Begley CG; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.
Condon SM; TetraLogic Pharmaceuticals Corporation , 343 Phoenixville Pike, Malvern, PA 19355, USA.

Cell Death Discov ; 3: 16046, 2017.

Article en En | MEDLINE | ID: mdl-28149532

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Cell Death Discov Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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