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Diffuse optical characterization of collagen absorption from 500 to 1700 nm.
Sekar, Sanathana Konugolu Venkata; Bargigia, Ilaria; Mora, Alberto Dalla; Taroni, Paola; Ruggeri, Alessandro; Tosi, Alberto; Pifferi, Antonio; Farina, Andrea.
Afiliación
  • Sekar SK; Politecnico di Milano, Dipartimento di Fisica, Milano, Italy.
  • Bargigia I; Istituto Italiano di Tecnologia, Center for Nano Science and Technology at Polimi, Milano, Italy.
  • Mora AD; Politecnico di Milano, Dipartimento di Fisica, Milano, Italy.
  • Taroni P; Politecnico di Milano, Dipartimento di Fisica, Milano, ItalycIstituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, Milano, Italy.
  • Ruggeri A; Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Milano, Italy.
  • Tosi A; Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Milano, Italy.
  • Pifferi A; Politecnico di Milano, Dipartimento di Fisica, Milano, ItalycIstituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, Milano, Italy.
  • Farina A; Istituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, Milano, Italy.
J Biomed Opt ; 22(1): 15006, 2017 01 01.
Article en En | MEDLINE | ID: mdl-28138693
Reduction in scattering, high absorption, and spectral features of tissue constituents above 1000 nm could help in gaining higher spatial resolution, penetration depth, and specificity for in vivo studies, opening possibilities of near-infrared diffuse optics in tissue diagnosis. We present the characterization of collagen absorption over a broadband range (500 to 1700 nm) and compare it with spectra presented in the literature. Measurements were performed using a time-domain diffuse optical technique. The spectrum was extracted by carefully accounting for various spectral distortion effects, due to sample and system properties. The contribution of several tissue constituents (water, lipid, collagen, oxy, and deoxy-hemoglobin) to the absorption properties of a collagen-rich in vivo bone location, such as radius distal in the 500- to 1700-nm wavelength region, is also discussed, suggesting bone diagnostics as a potential area of interest.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colágeno / Absorción Ocular Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Biomed Opt Asunto de la revista: ENGENHARIA BIOMEDICA / OFTALMOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colágeno / Absorción Ocular Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Biomed Opt Asunto de la revista: ENGENHARIA BIOMEDICA / OFTALMOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos