[Cloning genes, induced by x-ray irradiation in rat liver cells]. / Klonirovanie genov, indutsiruemykh rentgenovskim oblucheniem v kletkakh pecheni krysy.
Mol Gen Mikrobiol Virusol
; (7): 35-8, 1989 Jul.
Article
en Ru
| MEDLINE
| ID: mdl-2811906
The library of cDNAs synthesized on poly(A)+ mRNA derived from rat liver after total X-irradiation of animals has been obtained. cDNA-clones (p gamma clones) representing sequences inducibly transcribed as a result of radiation treatment were isolated by differential screening. The increased expression of p gamma mRNAs was observed during the period from 6 to 24 h after irradiation by 3-6 Gy dose. It was concluded that p gamma mRNAs do not code for the liver-specified proteins because these mRNAs are also present in the rat fibroblasts. We suggest that p gamma genes are involved in the pathways of DNA-repair system.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ADN
/
Expresión Génica
/
Clonación Molecular
/
Hígado
Límite:
Animals
Idioma:
Ru
Revista:
Mol Gen Mikrobiol Virusol
Asunto de la revista:
BIOLOGIA MOLECULAR
/
MICROBIOLOGIA
/
VIROLOGIA
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Rusia