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Treating patients with Dynamic Wave Arc: First clinical experience.
Burghelea, Manuela; Verellen, Dirk; Dhont, Jennifer; Hung, Cecilia; Gevaert, Thierry; Van den Begin, Robbe; Collen, Christine; Poels, Kenneth; Tournel, Koen; Boussaer, Marlies; Jaudet, Cyril; Reynders, Truus; Simon, Viorica; de Ridder, Mark.
Afiliación
  • Burghelea M; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium; Brainlab AG, Feldkirchen, Germany; Babes Bolyai University, Faculty of Physics, Cluj-Napoca, Romania. Electronic address: manuela.buleteanu@yahoo.com.
  • Verellen D; GZA Ziekenhuizen, Sint Augustinus - Iridium Kankernetwerk Antwerpen, VUB, Faculty of Medicine and Pharmacy, Brussels, Belgium.
  • Dhont J; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Hung C; Brainlab AG, Feldkirchen, Germany.
  • Gevaert T; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Van den Begin R; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Collen C; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Poels K; Department of Radiation Oncology, University Hospitals Leuven, Belgium.
  • Tournel K; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Boussaer M; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Jaudet C; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Reynders T; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
  • Simon V; Babes Bolyai University, Faculty of Physics, Cluj-Napoca, Romania.
  • de Ridder M; Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Department of Radiotherapy, Belgium.
Radiother Oncol ; 122(3): 347-351, 2017 03.
Article en En | MEDLINE | ID: mdl-28117078
BACKGROUND AND PURPOSE: Dynamic Wave Arc (DWA) is a system-specific noncoplanar arc technique that combines synchronized gantry-ring rotation with D-MLC optimization. This paper presents the clinical workflow, quality assurance program, and reports the geometric and dosimetric results of the first patient cohort treated with DWA. METHODS AND MATERIALS: The RayStation TPS was clinically integrated on the Vero SBRT platform for DWA treatments. The first 15 patients treated with DWA represent a broad range of treatment sites: breast boost, prostate, lung SBRT and bone metastases, which allowed us to explore the potentials and assess the limitations of the current DWA site-specific template solution. For the DWA verification a variety of QA equipment was used, from 3D diode array to an anthropomorphic end-to-end phantom. The geometric accuracy of each arc was verified with an independent orthogonal fluoroscopy method. RESULTS: The average beam-on delivery time was 3min, ranging from 1.22min to 8.82min. All patient QAs passed our institutional clinical criteria of gamma index. For both EBT3 film and Delta4 measurements, DWA planned versus delivered dose distributions presented an average agreement above 97%. An overall mean gantry-ring geometric deviation of -0.03°±0.46° and 0.18°±0.26° was obtained, respectively. CONCLUSION: For the first time, DWA has been translated into the clinic and used to treat various treatment sides. DWA has been successfully added to the noncoplanar rotational IMRT techniques arsenal, allowing additional flexibility in dose shaping while preserving dosimetrically robust delivery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias Óseas / Neoplasias de la Mama / Radioterapia de Intensidad Modulada / Neoplasias Pulmonares Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Radiother Oncol Año: 2017 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Neoplasias Óseas / Neoplasias de la Mama / Radioterapia de Intensidad Modulada / Neoplasias Pulmonares Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Radiother Oncol Año: 2017 Tipo del documento: Article Pais de publicación: Irlanda