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A single-centre experience of Roux-en-Y enteric drainage for pancreas transplantation.
Amin, Irum; Butler, Andrew J; Defries, Gail; Russell, Neil K; Harper, Simon J F; Jah, Asif; Saeb-Parsy, Kourosh; Pettigrew, Gavin J; Watson, Christopher J E.
Afiliación
  • Amin I; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Butler AJ; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Defries G; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Russell NK; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Harper SJ; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Jah A; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Saeb-Parsy K; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Pettigrew GJ; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
  • Watson CJ; Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Transpl Int ; 30(4): 410-419, 2017 Apr.
Article en En | MEDLINE | ID: mdl-28109015
Exocrine drainage following pancreas transplantation can be achieved by drainage into the bladder or bowel, the latter typically by direct duodeno-jejunostomy; the use of Roux-en-Y enteric drainage is uncommon. We report a retrospective analysis of a single-centre experience of Roux-en-Y enteric drainage following pancreas transplantation. Over a 14-year period (2001-2015), 204 consecutive adult pancreas transplants were performed (96.6% simultaneous pancreas and kidney transplants), of which 26.0% were from donors after circulatory death (DCD). During a median follow-up of 67 months (range 13-183 months), 14 (6.9%) recipients experienced complications related to their enteric drainage. Complications during follow-up included early enteric anastomotic haemorrhage (five patients), non-anastomotic enteric bleeding (one patient), small bowel obstruction (four patients) and graft duodenal perforation (two within 6 weeks, five beyond 12 months). No recipient lost their graft as a direct result of complications related to enteric drainage. Patient and pancreas graft survival at 1 year was 99.0% and 94.0% and at 5 years 91.3% and 84.9%, respectively. We conclude that Roux-en-Y enteric drainage following pancreas transplantation is a safe and effective procedure and facilitates graft salvage in the event of graft duodenal perforation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anastomosis en-Y de Roux / Drenaje / Trasplante de Páncreas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transpl Int Asunto de la revista: TRANSPLANTE Año: 2017 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anastomosis en-Y de Roux / Drenaje / Trasplante de Páncreas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Transpl Int Asunto de la revista: TRANSPLANTE Año: 2017 Tipo del documento: Article Pais de publicación: Suiza