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The assessment of macular electrophysiology and macular morphology in patients with vitiligo.
Aydin, Rukiye; Ozsutcu, Mustafa; Erdur, Sevil Karaman; Dikkaya, Funda; Balevi, Ali; Ozbek, Merve; Senturk, Fevzi.
Afiliación
  • Aydin R; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey. drrukiyeaydin@gmail.com.
  • Ozsutcu M; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey.
  • Erdur SK; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey.
  • Dikkaya F; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey.
  • Balevi A; Department of Dermatology, Istanbul Medipol University, Istanbul, Turkey.
  • Ozbek M; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey.
  • Senturk F; Department of Ophthalmology, Istanbul Medipol University, TEM Avrupa Otoyolu Cikisi, 34214, Bagcilar, Istanbul, Turkey.
Int Ophthalmol ; 38(1): 233-239, 2018 Feb.
Article en En | MEDLINE | ID: mdl-28108905
PURPOSE: We aimed to analyze the electrophysiologic function and morphology of macula in vitiligo patients. METHODS: Seventeen patients with vitiligo and 11 healthy subjects were studied. All participants underwent multifocal electroretinography (mfERG) and spectral domain optical coherence tomography (SD-OCT) evaluations. The mfERG (P1 mfERG responses central and peripheral) and retinal layer segmentation parameters (nine ETDRS subfields) were compared in vitiligo and control groups. RESULTS: The mean P1 response amplitudes were significantly decreased in central and peripheral rings of the fovea in patients with vitiligo compared with controls (p = 0.002 and p = 0.006, respectively). There was a tendency toward a prolonged mean implicit time for both central and peripheral in patients with vitiligo compared to controls, however, with no statistical significance (p = 0.453 and p = 0.05, respectively). There was no statistically significant difference in all retinal layers thickness between two groups. CONCLUSION: In patients with vitiligo, while photoreceptor segment preserved in SD-OCT, mfERG reduced showing potential decline in central retinal function. This study showed a potential decline in central retinal function in patients with vitiligo even if they have normal fundus appearance and SD-OCT findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitíligo / Agudeza Visual / Electrorretinografía / Mácula Lútea Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Ophthalmol Año: 2018 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitíligo / Agudeza Visual / Electrorretinografía / Mácula Lútea Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Ophthalmol Año: 2018 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos