Clinicopathological features, diagnosis, and treatment of IgA nephropathy with minimal change disease related to exposure to mercury-containing cosmetics: a case reportâ©.
Clin Nephrol
; 87 (2017)(4): 196-201, 2017 Apr.
Article
en En
| MEDLINE
| ID: mdl-28102816
AIM: Membranous nephropathy and minimal change disease (MCD) have been involved in mercury-induced nephrotic syndrome. IgA nephropathy is not known to be a common pathological type. In the present article, we report a case of IgA nephropathy with MCD following exposure to mercury-containing skin lightening cream. MATERIAL AND METHODS: The patient was a 39-year-old woman who presented with nephrotic syndrome. She had a 6-month history of using as many as 8 kinds of skin-lightening creams, and urinary mercury excretion was high. Renal biopsy revealed IgA nephropathy with MCD. The use of cosmetics was stopped and chelation therapy was given. After 4 courses (1 month) of chelation therapy, there was a complete remission of proteinuria and hematuria, and urine tests remained normal during the 5-year follow-up period. RESULTS AND CONCLUSIONS: The unique clinical and pathological features of IgA nephropathy with MCD had raised the controversial question of whether MCD and IgA deposition are separate entities or a common pathophysiology. Repeated renal biopsy and similar cases were helpful and should be carried out as far as possible.â©.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Preparaciones para Aclaramiento de la Piel
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Glomerulonefritis por IGA
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Intoxicación por Mercurio
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Nefrosis Lipoidea
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Clin Nephrol
Año:
2017
Tipo del documento:
Article
Pais de publicación:
Alemania