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Metformin restores the mitochondrial network and reverses mitochondrial dysfunction in Down syndrome cells.
Izzo, Antonella; Nitti, Maria; Mollo, Nunzia; Paladino, Simona; Procaccini, Claudio; Faicchia, Deriggio; Calì, Gaetano; Genesio, Rita; Bonfiglio, Ferdinando; Cicatiello, Rita; Polishchuk, Elena; Polishchuk, Roman; Pinton, Paolo; Matarese, Giuseppe; Conti, Anna; Nitsch, Lucio.
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  • Izzo A; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Nitti M; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Mollo N; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44100 Ferrara, Italy.
  • Paladino S; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Procaccini C; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Faicchia D; Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
  • Calì G; Department of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
  • Genesio R; Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
  • Bonfiglio F; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Cicatiello R; Department of Biosciences and Nutrition, Karolinska Institutet, 17177 Stockholm, Sweden.
  • Polishchuk E; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Polishchuk R; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Pinton P; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Matarese G; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44100 Ferrara, Italy.
  • Conti A; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
  • Nitsch L; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Hum Mol Genet ; 26(6): 1056-1069, 2017 03 15.
Article en En | MEDLINE | ID: mdl-28087733
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Down / Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma / Metformina / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Down / Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma / Metformina / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido