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BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.
López-García, Carlos; Sansregret, Laurent; Domingo, Enric; McGranahan, Nicholas; Hobor, Sebastijan; Birkbak, Nicolai Juul; Horswell, Stuart; Grönroos, Eva; Favero, Francesco; Rowan, Andrew J; Matthews, Nicholas; Begum, Sharmin; Phillimore, Benjamin; Burrell, Rebecca; Oukrif, Dahmane; Spencer-Dene, Bradley; Kovac, Michal; Stamp, Gordon; Stewart, Aengus; Danielsen, Havard; Novelli, Marco; Tomlinson, Ian; Swanton, Charles.
Afiliación
  • López-García C; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Sansregret L; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Domingo E; Oxford Centre for Cancer Gene Research, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN UK; Department of Oncology, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • McGranahan N; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC2E 6DD, UK.
  • Hobor S; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Birkbak NJ; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC2E 6DD, UK.
  • Horswell S; Bioinformatics Science Technology Platform, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Grönroos E; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Favero F; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Cancer System Biology, Centre for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.
  • Rowan AJ; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Matthews N; Advanced Sequencing Facility, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Begum S; Advanced Sequencing Facility, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Phillimore B; Advanced Sequencing Facility, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Burrell R; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Oukrif D; Research Department of Pathology, University College London Medical School, University Street, London WC1E 6JJ, UK.
  • Spencer-Dene B; Experimental Histopathology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Kovac M; Oxford Centre for Cancer Gene Research, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN UK.
  • Stamp G; Experimental Histopathology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Stewart A; Bioinformatics Science Technology Platform, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Danielsen H; Institute for Cancer Genetics and Informatics, Norwegian Radium Hospital, Oslo University Hospital, Ullernchausseen 70, 0379 Oslo, Norway.
  • Novelli M; Research Department of Pathology, University College London Medical School, University Street, London WC1E 6JJ, UK.
  • Tomlinson I; Oxford Centre for Cancer Gene Research, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN UK.
  • Swanton C; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Translational Cancer Therapeutics Laboratory, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC2E 6DD, UK. Electronic address: charles.swanton
Cancer Cell ; 31(1): 79-93, 2017 01 09.
Article en En | MEDLINE | ID: mdl-28073006
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Cisteína Endopeptidasas / Neoplasias Colorrectales / Proteínas de Unión al ADN / Caspasa 2 / Aneuploidia Tipo de estudio: Prognostic_studies Límite: Aged / Aged80 / Animals / Humans / Middle aged Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Cisteína Endopeptidasas / Neoplasias Colorrectales / Proteínas de Unión al ADN / Caspasa 2 / Aneuploidia Tipo de estudio: Prognostic_studies Límite: Aged / Aged80 / Animals / Humans / Middle aged Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos