No association between non-bullous skin reactions from lamotrigine and heterozygosity of UGT1A4 genetic variants *2(P24T) or *3(L48V) in Norwegian patients.

Shirzadi, Maryam; Reimers, Arne; Helde, Grethe; Sjursen, Wenche; Brodtkorb, Eylert

Shirzadi, Maryam; Reimers, Arne; Helde, Grethe; Sjursen, Wenche; Brodtkorb, Eylert.

Afiliación

Shirzadi M; Department of Neurology and Clinical Neurophysiology, St Olav's Hospital, Trondheim, Norway; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway. Electronic address: maryam.shirzadi@gmail.com.
Reimers A; Department of Clinical Pharmacology, St Olav's Hospital, Trondheim, Norway; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.
Helde G; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.
Sjursen W; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway; Department of Pathology and Medical Genetics, St Olav's Hospital, Trondheim, Norway.
Brodtkorb E; Department of Neurology and Clinical Neurophysiology, St Olav's Hospital, Trondheim, Norway; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway.

Seizure ; 45: 169-171, 2017 Feb.

Article en En | MEDLINE | ID: mdl-28068583

Asunto(s)

Anticonvulsivantes/uso terapéutico; Epilepsia/tratamiento farmacológico; Glucuronosiltransferasa/genética; Farmacogenética; Polimorfismo de Nucleótido Simple/genética; Enfermedades de la Piel/inducido químicamente; Triazinas/efectos adversos; Adolescente; Adulto; Anciano; Niño; Preescolar; Femenino; Genotipo; Humanos; Lactante; Lamotrigina; Masculino; Persona de Mediana Edad; Noruega; Adulto Joven

Palabras clave

Cutaneous adverse reaction; Lamotrigine; Polymorphisms; Serum concentration; UGT1A4

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Farmacogenética / Enfermedades de la Piel / Triazinas / Glucuronosiltransferasa / Polimorfismo de Nucleótido Simple / Epilepsia / Anticonvulsivantes Tipo de estudio: Risk_factors_studies Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Seizure Asunto de la revista: NEUROLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido

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