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Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Shirai, Cara Lunn; White, Brian S; Tripathi, Manorama; Tapia, Roberto; Ley, James N; Ndonwi, Matthew; Kim, Sanghyun; Shao, Jin; Carver, Alexa; Saez, Borja; Fulton, Robert S; Fronick, Catrina; O'Laughlin, Michelle; Lagisetti, Chandraiah; Webb, Thomas R; Graubert, Timothy A; Walter, Matthew J.
Afiliación
  • Shirai CL; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • White BS; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Tripathi M; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Tapia R; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Ley JN; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Ndonwi M; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Kim S; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Shao J; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Carver A; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
  • Saez B; Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA.
  • Fulton RS; McDonnell Genome Institute, Washington University, St Louis, Missouri 63108, USA.
  • Fronick C; McDonnell Genome Institute, Washington University, St Louis, Missouri 63108, USA.
  • O'Laughlin M; McDonnell Genome Institute, Washington University, St Louis, Missouri 63108, USA.
  • Lagisetti C; SRI International, Bioscience Division, Menlo Park, California 94025, USA.
  • Webb TR; SRI International, Bioscience Division, Menlo Park, California 94025, USA.
  • Graubert TA; Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA.
  • Walter MJ; Division of Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Nat Commun ; 8: 14060, 2017 01 09.
Article en En | MEDLINE | ID: mdl-28067246
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Empalme del ARN / Empalmosomas / Ciclohexilaminas / Factor de Empalme U2AF / Mutación Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Espiro / Empalme del ARN / Empalmosomas / Ciclohexilaminas / Factor de Empalme U2AF / Mutación Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido