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Quantum-classical model of retinal photoisomerization reaction in visual pigment rhodopsin.
Lakhno, V D; Shigaev, A S; Feldman, T B; Nadtochenko, V A; Ostrovsky, M A.
Afiliación
  • Lakhno VD; Institute of Mathematical Problems of Biology, Russian Academy of Sciences-branch of Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia.
  • Shigaev AS; Institute of Mathematical Problems of Biology, Russian Academy of Sciences-branch of Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia. shials@rambler.ru.
  • Feldman TB; Moscow State University, Moscow, 119991, Russia.
  • Nadtochenko VA; Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 117977, Russia.
  • Ostrovsky MA; Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, 119991, Russia.
Dokl Biochem Biophys ; 471(1): 435-439, 2016 Nov.
Article en En | MEDLINE | ID: mdl-28058680
A quantum-classical model of photoisomerization of the visual pigment rhodopsin chromophore is proposed. At certain (and more realistic) parameter value combinations, the model is shown to accurately reproduce a number of independent experimental data on the photoreaction dynamics: the quantum yield, the time to reach the point of conical intersection of potential energy surfaces, the termination time of the evolution of quantum subsystem, as well as the characteristic low frequencies of retinal molecular lattice fluctuations during photoisomerization. In addition, the model behavior is in good accordance with experimental data about coherence and local character of quantum transition.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Teoría Cuántica / Rodopsina / Vitamina A / Modelos Teóricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Dokl Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Teoría Cuántica / Rodopsina / Vitamina A / Modelos Teóricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Dokl Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos