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Assessing adherence to multiple medications and in daily life among patients with multimorbidity.
Inauen, Jennifer; Bierbauer, Walter; Lüscher, Janina; König, Claudia; Tobias, Robert; Ihle, Andreas; Zimmerli, Lukas; Holzer, Barbara M; Battegay, Edouard; Siebenhüner, Klarissa; Kliegel, Matthias; Scholz, Urte.
Afiliación
  • Inauen J; a Department of Psychology , Columbia University , New York , NY , USA.
  • Bierbauer W; b Department of Psychology , University of Zurich , Zurich , Switzerland.
  • Lüscher J; c Center of Competence Multimorbidity, University of Zurich , Zurich , Switzerland.
  • König C; b Department of Psychology , University of Zurich , Zurich , Switzerland.
  • Tobias R; g University Research Priority Program 'Dynamics of Healthy Aging', University of Zurich , Zurich , Switzerland.
  • Ihle A; b Department of Psychology , University of Zurich , Zurich , Switzerland.
  • Zimmerli L; b Department of Psychology , University of Zurich , Zurich , Switzerland.
  • Holzer BM; g University Research Priority Program 'Dynamics of Healthy Aging', University of Zurich , Zurich , Switzerland.
  • Battegay E; b Department of Psychology , University of Zurich , Zurich , Switzerland.
  • Siebenhüner K; d Department of Psychology , University of Geneva , Geneva , Switzerland.
  • Kliegel M; h Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva , Geneva , Switzerland.
  • Scholz U; i Swiss National Center of Competences in Research LIVES-Overcoming Vulnerability: Life Course Perspectives , Lausanne , Switzerland.
Psychol Health ; 32(10): 1233-1248, 2017 Oct.
Article en En | MEDLINE | ID: mdl-28043163
OBJECTIVE: Chronic conditions often require multiple medication intake. However, past research has focused on assessing overall adherence or adherence to a single index medication only. This study explored adherence measures for multiple medication intake, and in daily life, among patients with multiple chronic conditions (i.e. multimorbidity). DESIGN: Eighty-four patients with multimorbidity and multiple-medication regimens completed three monthly panel questionnaires. A randomly assigned subsample additionally completed a 30-day daily diary. MAIN OUTCOME MEASURE: The Non-Adherence Report; a brief self-report measure of adherence to each prescribed medication (NAR-M), and in daily life. We further assessed the Medication Adherence Report Scale (MARS), and a subsample of participants were randomised to electronic adherence monitoring. RESULTS: The NAR-M indicated M = 94.7% adherence at Time 1 (SD = 9.3%). The NAR-M was significantly correlated with the MARS (rt1 = .52, rt2 = .57, and rt3 = .65; p < .001), and in tendency with electronically assessed adherence (rt2 = .45, rt3 = .46, p < .10). Variance components analysis indicated that between-person differences accounted for 10.2% of the variance in NAR-M adherence rates, whereas 22.9% were attributable to medication by person interactions. CONCLUSION: This study highlights the importance and feasibility of studying adherence to multiple medications differentially, and in daily life. Future studies may use these measures to investigate within-person and between-medication differences in adherence.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Crónica / Polifarmacia / Cumplimiento de la Medicación / Multimorbilidad Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Psychol Health Asunto de la revista: PSICOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Crónica / Polifarmacia / Cumplimiento de la Medicación / Multimorbilidad Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Psychol Health Asunto de la revista: PSICOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido