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Infiltrative thyrotoxicosis: an unusual case of diffuse large B cell lymphoma.
McCarthy, Michael T; Keyes, Michael; O'Hare, James; Shine, Neville; Gupta, Rajnish K.
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  • McCarthy MT; Specialist Registrar in Medical Oncology, University Hospital Limerick , Limerick , Ireland.
  • Keyes M; Senior House Officer in General Medicine, University Hospital Limerick , Limerick , Ireland.
  • O'Hare J; Consultant Endocrinologist, University Hospital Limerick , Limerick , Ireland.
  • Shine N; Consultant ENT Surgeon, University Hospital Limerick , Limerick , Ireland.
  • Gupta RK; Consultant Medical Oncologist, University Hospital Limerick , Limerick , Ireland.
Oxf Med Case Reports ; 2016(11): omw082, 2016 Nov.
Article en En | MEDLINE | ID: mdl-28031847
Thyrotoxicosis is most commonly caused by Graves' disease, toxic multinodular goitre, a functioning thyroid adenoma, or thyroiditis. Extrinsic infiltrative conditions affecting the thyroid gland are typically destructive, and associated with thyroid hypofunction. We describe the case of a 61-year-old woman who presented to our hospital with symptoms of thyrotoxicosis, neck swelling and thyroid function tests consistent with hyperthyroidism. An ultrasound revealed a multinodular goitre with retrosternal extension, but CT imaging suggested thyroid gland infiltration, with cervical lymphadenopathy. An excisional lymph node biopsy confirmed the diagnosis of diffuse large B cell lymphoma causing infiltrative thyrotoxicosis. Treatment with six cycles of Rituximab-CHOP lead to rapid normalization of symptoms, imaging, and thyroid function.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oxf Med Case Reports Año: 2016 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oxf Med Case Reports Año: 2016 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Reino Unido