Activation of PPAR-&#945; in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure.

Kaimoto, Satoshi; Hoshino, Atsushi; Ariyoshi, Makoto; Okawa, Yoshifumi; Tateishi, Shuhei; Ono, Kazunori; Uchihashi, Motoki; Fukai, Kuniyoshi; Iwai-Kanai, Eri; Matoba, Satoaki

Activation of PPAR-α in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure.

Kaimoto, Satoshi; Hoshino, Atsushi; Ariyoshi, Makoto; Okawa, Yoshifumi; Tateishi, Shuhei; Ono, Kazunori; Uchihashi, Motoki; Fukai, Kuniyoshi; Iwai-Kanai, Eri; Matoba, Satoaki.

Afiliación

Kaimoto S; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Hoshino A; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Ariyoshi M; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Okawa Y; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Tateishi S; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Ono K; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Uchihashi M; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Fukai K; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Iwai-Kanai E; Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji, Kyoto, Japan; and.
Matoba S; Faculty of Health Care, Tenri Health Care University, Nara, Japan.

Am J Physiol Heart Circ Physiol ; 312(2): H305-H313, 2017 Feb 01.

Article en En | MEDLINE | ID: mdl-28011586

Asunto(s)

Metabolismo Energético/genética; Insuficiencia Cardíaca/genética; Contracción Miocárdica/genética; Miocardio/metabolismo; PPAR alfa/genética; Disfunción Ventricular Izquierda/genética; Animales; Aorta/cirugía; Western Blotting; Modelos Animales de Enfermedad; Ecocardiografía; Metabolismo Energético/efectos de los fármacos; Ácidos Grasos/metabolismo; Glucosa/metabolismo; Insuficiencia Cardíaca/metabolismo; Insuficiencia Cardíaca/fisiopatología; Masculino; Ratones; Ratones Transgénicos; Contracción Miocárdica/efectos de los fármacos; Oxidación-Reducción; PPAR alfa/agonistas; Fosfatos/metabolismo; Pirimidinas/farmacología; Reacción en Cadena en Tiempo Real de la Polimerasa; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Disfunción Ventricular Izquierda/metabolismo; Disfunción Ventricular Izquierda/fisiopatología

Palabras clave

PPAR-α; energy metabolism; fatty acid oxidation; heart failure

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disfunción Ventricular Izquierda / PPAR alfa / Metabolismo Energético / Insuficiencia Cardíaca / Contracción Miocárdica / Miocardio Límite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos

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