Combined gene therapy with vascular endothelial growth factor plus apelin in a chronic cerebral hypoperfusion model in rats.

Hiramatsu, Masafumi; Hishikawa, Tomohito; Tokunaga, Koji; Kidoya, Hiroyasu; Nishihiro, Shingo; Haruma, Jun; Shimizu, Tomohisa; Takasugi, Yuji; Shinji, Yukei; Sugiu, Kenji; Takakura, Nobuyuki; Date, Isao

Hiramatsu, Masafumi; Hishikawa, Tomohito; Tokunaga, Koji; Kidoya, Hiroyasu; Nishihiro, Shingo; Haruma, Jun; Shimizu, Tomohisa; Takasugi, Yuji; Shinji, Yukei; Sugiu, Kenji; Takakura, Nobuyuki; Date, Isao.

Afiliación

Hiramatsu M; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Hishikawa T; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Tokunaga K; Department of Neurosurgery, Okayama City Hospital, Okayama; and.
Kidoya H; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Nishihiro S; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Haruma J; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Shimizu T; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Takasugi Y; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Shinji Y; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Sugiu K; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Takakura N; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Date I; Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

J Neurosurg ; 127(3): 679-686, 2017 Sep.

Article en En | MEDLINE | ID: mdl-28009234

Asunto(s)

Apelina/uso terapéutico; Isquemia Encefálica/terapia; Terapia Genética; Enfermedad de Moyamoya/terapia; Factor A de Crecimiento Endotelial Vascular/uso terapéutico; Animales; Enfermedad Crónica; Terapia Combinada; Modelos Animales de Enfermedad; Masculino; Ratas; Ratas Wistar

Palabras clave

Ang-1 = angiopoietin-1; CBF = cerebral blood flow; CCA = common carotid artery; CCAO = CCA occlusion; EC = endothelial cells; ELISA = enzyme-linked immunosorbent assay; EMS = encephalo-myo-synangiosis; MMD = moyamoya disease; PBS = phosphate-buffered saline; PFA = paraformaldehyde; RECA-1 = mouse monoclonal anti-EC antibody; VEGF = vascular endothelial growth factor; apelin; gene therapy; moyamoya disease; revascularization; vascular endothelial growth factor

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia Genética / Isquemia Encefálica / Factor A de Crecimiento Endotelial Vascular / Apelina / Enfermedad de Moyamoya Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Neurosurg Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google